The estrogen-regulated anterior gradient 2 (AGR2) protein in breast cancer: a potential drug target and biomarker

ML Salmans, F Zhao, B Andersen - Breast Cancer Research, 2013 - Springer
Initially discovered as an estrogen-responsive gene in breast cancer cell lines, anterior
gradient 2 (AGR2) is a developmentally regulated gene belonging to the protein disulfide …

AGR2, ERp57/GRP58, and some other human protein disulfide isomerases

SS Shishkin, LS Eremina, LI Kovalev… - Biochemistry (Moscow …, 2013 - Springer
This review considers the major features of human proteins AGR2 and ERp57/GRP58 and
of other members of the protein disulfide isomerase (PDI) family. The ability of both AGR2 …

[PDF][PDF] Effect of type 2 diabetes on risk for malignancies includes hepatocellular carcinoma in chronic hepatitis C

Y Arase, M Kobayashi, F Suzuki, Y Suzuki… - …, 2013 - Wiley Online Library
The aim of this retrospective cohort study was to assess the cumulative development
incidence and predictive factors for malignancies after the termination of interferon (IFN) …

Quantitative proteomics reveals that enzymes of the ketogenic pathway are associated with prostate cancer progression

P Saraon, D Cretu, N Musrap… - Molecular & Cellular …, 2013 - mcponline.org
Prostate cancer is the most common malignancy and the second leading cause of cancer-
related deaths in men. One common treatment is androgen-deprivation therapy, which …

SETDB1 accelerates tumourigenesis by regulating the WNT signalling pathway

QY Sun, LW Ding, JF **ao, W Chien… - The Journal of …, 2015 - Wiley Online Library
We investigated the oncogenic role of SETDB1, focusing on non‐small cell lung cancer
(NSCLC), which has high expression of this protein. A total of 387 lung cancer cases were …

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2

S Li, Y Wang, Y Zhang, MM Lu, FJ DeMayo… - …, 2012 - journals.biologists.com
The molecular pathways regulating cell lineage determination and regeneration in epithelial
tissues are poorly understood. The secretory epithelium of the lung is required for production …

Quantitative secretomic analysis identifies extracellular protein factors that modulate the metastatic phenotype of non-small cell lung cancer

R Hu, KE Huffman, M Chu, Y Zhang… - Journal of proteome …, 2016 - ACS Publications
Lung cancer is the leading cause of cancer-related deaths for men and women in the United
States, with non-small cell lung cancer (NSCLC) representing 85% of all diagnoses. Late …

Anterior gradient 2 (AGR2): blood‐based biomarker elevated in metastatic prostate cancer associated with the neuroendocrine phenotype

K Kani, PD Malihi, Y Jiang, H Wang, Y Wang… - The …, 2013 - Wiley Online Library
Abstract BACKGROUND Anterior gradient 2 (AGR2) is associated with metastatic
progression in prostate cancer cells as well as other normal and malignant tissues. We …

Immunohistochemical panel for distinguishing esophageal adenocarcinoma from squamous cell carcinoma: a combination of p63, cytokeratin 5/6, MUC5AC, and …

MA DiMaio, S Kwok, KD Montgomery, AW Lowe… - Human pathology, 2012 - Elsevier
Distinguishing adenocarcinoma and squamous cell carcinoma of the esophagus is often
based on morphological criteria and can be difficult in small biopsies. We analyzed …

[HTML][HTML] Prostate cancer research: tools, cell types, and molecular targets

AY Liu - Frontiers in Oncology, 2024 - frontiersin.org
Multiple cancer cell types are found in prostate tumors. They are either luminal-like
adenocarcinoma or less luminal-like and more stem-like non-adenocarcinoma and small …