Right ventricular failure

BA Houston, EL Brittain… - New England Journal of …, 2023 - Mass Medical Soc
Right Ventricular Failure | New England Journal of Medicine Skip to main content The New
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Treatment algorithm for pulmonary arterial hypertension

KM Chin, SP Gaine, C Gerges, ZC **g… - European …, 2024 - publications.ersnet.org
Pulmonary arterial hypertension leads to significant impairment in haemodynamics, right
heart function, exercise capacity, quality of life and survival. Current therapies have …

Novel therapeutic approaches targeting the renin-angiotensin system and associated peptides in hypertension and heart failure

LB Arendse, AHJ Danser, M Poglitsch, RM Touyz… - Pharmacological …, 2019 - Elsevier
Despite the success of renin-angiotensin system (RAS) blockade by angiotensin-converting
enzyme (ACE) inhibitors and angiotensin II type 1 receptor (AT 1 R) blockers, current …

Endothelin: 30 years from discovery to therapy

M Barton, M Yanagisawa - Hypertension, 2019 - Am Heart Assoc
Discovered in 1987 as a potent endothelial cell–derived vasoconstrictor peptide, endothelin-
1 (ET-1), the predominant member of the endothelin peptide family, is now recognized as a …

Pulmonary hypertension due to left heart disease: diagnosis, pathophysiology, and therapy

MS Al-Omary, S Sugito, AJ Boyle, AL Sverdlov… - …, 2020 - Am Heart Assoc
Pulmonary hypertension (PH) due to left heart disease (LHD) is the most common type of PH
and is defined as mean pulmonary artery systolic pressure of> 20 mm Hg and pulmonary …

Endothelin-1 levels and cardiovascular events

M Jankowich, G Choudhary - Trends in cardiovascular medicine, 2020 - Elsevier
Circulating plasma levels of endothelin-1 and related peptides generated during the
synthesis of endothelin-1 from its precursor molecule pre-proendothelin-1 have been widely …

Endothelin-1, outcomes in patients with heart failure and reduced ejection fraction, and effects of dapagliflozin: findings from DAPA-HF

SE Yeoh, KF Docherty, RT Campbell, PS Jhund… - Circulation, 2023 - Am Heart Assoc
Background: ET-1 (endothelin-1) is implicated in the pathophysiology of heart failure and
renal disease. Its prognostic importance and relationship with kidney function in patients …

Edema formation in congestive heart failure and the underlying mechanisms

Z Abassi, EE Khoury, T Karram… - Frontiers in cardiovascular …, 2022 - frontiersin.org
Congestive heart failure (HF) is a complex disease state characterized by impaired
ventricular function and insufficient peripheral blood supply. The resultant reduced blood …

Pulmonary hypertension associated with left heart disease: Updated Recommendations of the Cologne Consensus Conference 2018

S Rosenkranz, IM Lang, R Blindt, D Bonderman… - International journal of …, 2018 - Elsevier
In the summer of 2016, delegates from the German Society of Cardiology (DGK), the
German Respiratory Society (DGP), and the German Society of Pediatric Cardiology (DGPK) …

[HTML][HTML] Targeting key inflammatory mechanisms underlying heart failure: a comprehensive review

A Papamichail, C Kourek, A Briasoulis… - International Journal of …, 2023 - mdpi.com
Inflammation is a major component of heart failure (HF), causing peripheral vasculopathy
and cardiac remodeling. High levels of circulating inflammatory cytokines in HF patients …