Our populations are aging. Some experts predict that 30% of hospital beds will soon be
occupied by osteoporosis patients. Statistics show that 20% of patients suffering from an …

A systematic analysis of results available from in vitro, in vivo and clinical trials on the effects
of biocompatible calcium phosphate (CaP) coatings is presented. An overview of the most …

Reconstruction of bony defects is challenging when conventional grafting methods are used
because of their intrinsic limitations (biological cost and/or biological properties). Bone …

Calcium phosphate (CaP) ceramics have been widely used for bone regeneration because
of their ability to induce osteogenesis. Surface properties, including chemical composition …

In the past thirty years, a number of biomaterials have shown the ability to induce bone
formation when implanted at heterotopic sites, an ability known as osteoinduction. Such …

In the process of bone regeneration, new bone formation is largely affected by physico-
chemical cues in the surrounding microenvironment. Tissue cells reside in a complex …

Today, the integration of medical and engineering principles for producing biological
replacements has attracted much attention. Tissue engineering is an interdisciplinary field …

Calcium phosphate bioceramics are widely used in orthopedic and dental applications and
porous scaffolds made of them are serious candidates in the field of bone tissue …

Some biomaterials are osteoinductive, that is, they are able to trigger the osteogenic process
by inducing the differentiation of mesenchymal stem cells to the osteogenic lineage …

Many studies have shown that certain biomaterials with specific porous structures can
induce bone formation in non-osseous sites without the need for osteoinductive …