The immunology of pregnancy is complex and poorly defined. During the complex process
of pregnancy, macrophages secrete many cytokines/chemokines and play pivotal roles in …

During placentation invasive extravillous trophoblasts (EVTs) migrate into the maternal
uterus and modify its vessels. In particular, remodeling of the spiral arteries by EVTs is …

Preeclampsia, defined as new-onset hypertension accompanied by proteinuria occurring at
20 weeks of gestation or later, is a leading cause of perinatal morbidity and mortality …

Fetal growth restriction (FGR) and preeclampsia (PE) are often associated with abnormal
maternal inflammation, deficient spiral artery (SA) remodeling, and altered uteroplacental …

Trophoblasts are important parts of the placenta and exert vital roles in the maternal‐foetal
crosstalk, and sufficient trophoblasts migration and invasion is critical for embryo …

Preeclampsia is an important complication in pregnancy, characterized by hypertension and
proteinuria in the second half of pregnancy. Generalized activation of the inflammatory …

Hypertension is the most frequent medical complication occurring during pregnancy. In this
chapter, we aim to address the genetic contribution to these disorders, with specific focus on …

In human pregnancy, successful placentation and remodelling of the uterine vasculature
require the integration of a number of stages, which are crucial for a healthy pregnancy. As …

BACKGROUND During pregnancy, maternal uterine spiral arteries (SAs) are remodelled
from minimal-flow, high-resistance vessels into larger diameter vessels with low resistance …

Macrophages are versatile cells that play a central role in innate and adaptive immunity and
participate in a wide variety of biological processes. In the uterine decidua, macrophages …