Polymeric micelles are demonstrating high potential as nanomedicines capable of
controlling the distribution and function of loaded bioactive agents in the body, effectively …

The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

The rapid expansion of the available genomic data continues to greatly impact biomedical
science and medicine. Fulfilling the clinical potential of genetic discoveries requires the …

The targeted and efficiency-oriented delivery of (therapeutic) nucleic acids raises hope for
successful gene therapy, ie, for the local and individual treatment of acquired and inherited …

Polycations such as polyethylenimine (PEI) are used in many novel nonviral vector designs
and there are continuous efforts to increase our mechanistic understanding of their …

Nanomedicine involves the use of nanoparticles for therapeutic and diagnostic purposes.
During the past two decades, a growing number of nanomedicines have received regulatory …

Nanocarriers have therapeutic potential to facilitate drug delivery, including biological
agents, small-molecule drugs, and nucleic acids. However, their efficiency is limited by …

In non-viral gene therapy, cationic polymers and lipids are frequently used to encapsulate
macromolecular therapeutics into nanoparticles. During their journey to deliver the cargo to …

The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

Using nanoparticles to deliver drugs to cells has the potential to revolutionize the treatment
of many diseases, including HIV, cancer, and diabetes. One of the major challenges facing …