This article reviews and synthesizes research on reward processing in schizophrenia, which
has begun to provide important insights into the cognitive and neural mechanisms …

A range of emotional and motivation impairments have long been clinically documented in
people with schizophrenia, and there has been a resurgence of interest in understanding …

Exposing mammals to early-life adverse events, including maternal separation or social
isolation, profoundly affects brain development and adult behaviour and may contribute to …

The past several years have seen a resurgence of interest in understanding the
psychological and neural bases of what are often referred to as “negative symptoms” in …

Several tests from the CANTAB neuropsychological test battery previously shown to be
sensitive to frontal lobe dysfunction were administered to a large group of normal volunteers …

This review summarizes evidence of dysregulated reward circuitry function in a range of
neurodevelopmental and psychiatric disorders and genetic syndromes. First, the …

OBJECTIVE: Although schizophrenia is generally regarded as an illness with onset in late
adolescence or early adult life, a sizeable minority of patients first become ill in middle or old …

Motivational and hedonic impairments are core aspects of a variety of types of
psychopathology. These impairments cut across diagnostic categories and may be critical to …

Patients with schizophrenia demonstrate deficits in motivation and learning that suggest
impairment in different aspects of the reward system. In this article, we present the results of …

Background Although intellectual and neurocognitive deficits accompany schizophrenia,
there are inconsistencies in the literature concerning issues of intellectual decline …