Worldwide use of RUCAM for causality assessment in 81,856 idiosyncratic DILI and 14,029 HILI cases published 1993–mid 2020: a comprehensive analysis
R Teschke, G Danan - Medicines, 2020 - mdpi.com
Background: A large number of idiosyncratic drug induced liver injury (iDILI) and herb
induced liver injury (HILI) cases of variable quality has been published but some are a …
induced liver injury (HILI) cases of variable quality has been published but some are a …
Drug-induced liver injury: highlights from a review of the 2015 literature
P Sarges, JM Steinberg, JH Lewis - Drug safety, 2016 - Springer
Numerous publications contributed to the expanding knowledge base about drug-induced
liver injury (DILI) in 2015. New findings from the US Drug Induced Liver Injury Network …
liver injury (DILI) in 2015. New findings from the US Drug Induced Liver Injury Network …
[HTML][HTML] Clinical outcomes following DAA therapy in patients with HCV-related cirrhosis depend on disease severity
LAP Krassenburg, R Maan, A Ramji, MP Manns… - Journal of …, 2021 - Elsevier
Background & Aims HCV-infected patients with cirrhosis achieve high sustained virological
response (SVR) rates with direct-acting antivirals (DAAs) even after hepatic …
response (SVR) rates with direct-acting antivirals (DAAs) even after hepatic …
Inhibition of oxidative stress and ALOX12 and NF-κB pathways contribute to the protective effect of baicalein on carbon tetrachloride-induced acute liver injury
This study investigates the protective effect of baicalein on carbon tetrachloride (CCl4)-
induced acute liver injury and the underlying molecular mechanisms. Mice were orally …
induced acute liver injury and the underlying molecular mechanisms. Mice were orally …
[PDF][PDF] Treatment of hepatitis C virus infection in patients with cirrhosis and predictive value of model for end‐stage liver disease: Analysis of data from the Hepa‐C …
C Fernandez Carrillo, S Lens, E Llop, JM Pascasio… - …, 2017 - Wiley Online Library
Direct‐acting antiviral agents (DAAs) are highly effective and well tolerated in patients with
chronic hepatitis C virus infection, including those with compensated cirrhosis. However …
chronic hepatitis C virus infection, including those with compensated cirrhosis. However …
Increased risk of venous thromboembolism in hospitalized patients with cirrhosis due to non-alcoholic steatohepatitis
JG Stine, BA Niccum, AN Zimmet… - Clinical and …, 2018 - journals.lww.com
Objective: Patients with cirrhosis are at increased risk for venous thromboembolism (VTE)
and portal vein thrombosis (PVT). Cirrhosis due to non-alcoholic steatohepatitis (NASH) …
and portal vein thrombosis (PVT). Cirrhosis due to non-alcoholic steatohepatitis (NASH) …
[PDF][PDF] Safety and efficacy of simeprevir/sofosbuvir in hepatitis C–infected patients with compensated and decompensated cirrhosis
V Saxena, L Nyberg, M Pauly, A Dasgupta… - …, 2015 - Wiley Online Library
Risks and benefits of simeprevir plus sofosbuvir (SIM+ SOF) in patients with advanced
cirrhosis are unknown. We assessed the safety and sustained virological responses (SVR) …
cirrhosis are unknown. We assessed the safety and sustained virological responses (SVR) …
Safety and effectiveness of direct-acting antiviral agents for treatment of patients with chronic hepatitis C virus infection and cirrhosis
R Maan, M van Tilborg, K Deterding, A Ramji… - Clinical …, 2016 - Elsevier
Background & Aims Direct-acting antivirals (DAAs) have revolutionized treatment for patients
with chronic hepatitis C virus (HCV) infection, leading to a high rates of sustained virologic …
with chronic hepatitis C virus (HCV) infection, leading to a high rates of sustained virologic …
Prevention and management of treatment failure to new oral hepatitis C drugs
L Benítez-Gutiérrez, P Barreiro, P Labarga… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: Chronic hepatitis C virus (HCV) infection has become a curable disease.
Sustained virologic response rates above 90% have been achieved with recommended …
Sustained virologic response rates above 90% have been achieved with recommended …
[HTML][HTML] Acute liver injury induced by carbon tetrachloride reversal by Gandankang aqueous extracts through nuclear factor erythroid 2-related factor 2 signaling …
Y Wei, H Wang, Y Fan, J Gu, X Zhang, X Gong… - … and Environmental Safety, 2023 - Elsevier
The aims of this study were to evaluated the effect and underlying mechanism of
Gandankang (GDK) aqueous extract in alleviating the acute liver injury induced by carbon …
Gandankang (GDK) aqueous extract in alleviating the acute liver injury induced by carbon …