ROS-induced lipid peroxidation modulates cell death outcome: mechanisms behind apoptosis, autophagy, and ferroptosis

B Wang, Y Wang, J Zhang, C Hu, J Jiang, Y Li… - Archives of …, 2023 - Springer
Reactive oxygen species (ROS) mediate lipid peroxidation and produce 4-hydroxynonenal
and other related products, which play an important role in the process of cell death …

Redox signaling by reactive electrophiles and oxidants

S Parvez, MJC Long, JR Poganik, Y Aye - Chemical reviews, 2018 - ACS Publications
The concept of cell signaling in the context of nonenzyme-assisted protein modifications by
reactive electrophilic and oxidative species, broadly known as redox signaling, is a uniquely …

[HTML][HTML] Mitochondrial dysfunction and oxidative stress in aging and cancer

AV Kudryavtseva, GS Krasnov, AA Dmitriev… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Aging and cancer are the most important issues to research. The population in the world is
growing older, and the incidence of cancer increases with age. There is no doubt about the …

Glutathione transferases

JD Hayes, JU Flanagan… - Annu. Rev. Pharmacol …, 2005 - annualreviews.org
▪ Abstract This review describes the three mammalian glutathione transferase (GST)
families, namely cytosolic, mitochondrial, and microsomal GST, the latter now designated …

Redox regulation of cell survival

D Trachootham, W Lu, MA Ogasawara… - Antioxidants & redox …, 2008 - liebertpub.com
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) play important roles in
regulation of cell survival. In general, moderate levels of ROS/RNS may function as signals …

Chemistry and biochemistry of lipid peroxidation products

F Guéraud, M Atalay, N Bresgen, A Cipak… - Free radical …, 2010 - Taylor & Francis
Oxidative stress and resulting lipid peroxidation is involved in various and numerous
pathological states including inflammation, atherosclerosis, neurodegenerative diseases …

[PDF][PDF] Lipid peroxidation, reactive oxygen species and antioxidative factors in the pathogenesis of gastric mucosal lesions and mechanism of protection against …

S Kwiecien, K Jasnos, M Magierowski… - J Physiol …, 2014 - jpp.krakow.pl
The gastric mucosa plays an important role in the physiological function of the stomach. This
mucosa acts as gastric barrier, which protects deeper located cells against the detrimental …

Lipid peroxidation of membrane phospholipids generates hydroxy-alkenals and oxidized phospholipids active in physiological and/or pathological conditions

A Catalá - Chemistry and physics of lipids, 2009 - Elsevier
Polyunsaturated fatty acids (PUFAs) and their metabolites have a variety of physiological
roles including: energy provision, membrane structure, cell signaling and regulation of gene …

Heme iron from meat and risk of colorectal cancer: a meta-analysis and a review of the mechanisms involved

NM Bastide, FHF Pierre, DE Corpet - Cancer prevention research, 2011 - AACR
Red meat and processed meat intake is associated with a risk of colorectal cancer, a major
cause of death in affluent countries. Epidemiological and experimental evidence supports …

Oxidative stress and covalent modification of protein with bioactive aldehydes

PA Grimsrud, H **e, TJ Griffin, DA Bernlohr - Journal of Biological …, 2008 - ASBMB
The term" oxidative stress" links the production of reactive oxygen species to a variety of
metabolic outcomes, including insulin resistance, immune dysfunction, and inflammation …