Exercise, stress, sleep and diet are four distinct but intertwined lifestyle factors that influence
the cardiovascular system. Abundant epidemiological, clinical and preclinical studies have …

Clonal hematopoiesis (CH) is an age-related process whereby hematopoietic stem and
progenitor cells (HSPCs) acquire mutations that lead to a proliferative advantage and clonal …

The signals and structure of the tissues in which leukocytes reside critically mould leukocyte
function and development and have challenged our fundamental understanding of how to …

Age is a predominant risk factor for acute kidney injury (AKI), yet the biological mechanisms
underlying this risk are largely unknown. Clonal hematopoiesis of indeterminate potential …

Abstract Purpose of Review To examine the epidemiological data on obesity and leukemia;
evaluate the effect of obesity on leukemia outcomes in childhood acute lymphoblastic …

Clonal hematopoiesis of indeterminate potential (CHIP) is a common bone marrow
abnormality induced by age‐related DNA mutations, which give rise to proinflammatory …

Knowledge on the myeloproliferative neoplasms (MPNs)–polycythemia vera (PV), essential
thrombocythemia (ET), primary myelofibrosis (PMF)–has accumulated since the discovery of …

OBJECTIVE Clonal hematopoiesis of indeterminate potential (CHIP) is an aging-related
accumulation of somatic mutations in hematopoietic stem cells, leading to clonal expansion …

Clonal hematopoiesis of indeterminate potential (CHIP) is characterized by the selective
expansion of hematopoietic stem and progenitor cells (HSPCs) carrying somatic mutations …

Somatic TP53 mutations are prevalent in normal tissue but little is known about their
association with cancer risk. Cervical liquid-based cytology (LBC), commonly known as Pap …