Leptospira and leptospirosis

B Adler, A de la Peña Moctezuma - Veterinary microbiology, 2010 - Elsevier
Leptospirosis is the most wide spread zoonosis worldwide; it is present in all continents
except Antarctica and evidence for the carriage of Leptospira has been found in virtually all …

Leptospira: the dawn of the molecular genetics era for an emerging zoonotic pathogen

AI Ko, C Goarant, M Picardeau - Nature Reviews Microbiology, 2009 - nature.com
Leptospirosis is a zoonotic disease that has emerged as an important cause of morbidity
and mortality among impoverished populations. One hundred years after the discovery of …

What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira

DE Fouts, MA Matthias, H Adhikarla… - PLoS neglected …, 2016 - journals.plos.org
Leptospirosis, caused by spirochetes of the genus Leptospira, is a globally widespread,
neglected and emerging zoonotic disease. While whole genome analysis of individual …

Leptospiral infection, pathogenesis and its diagnosis—A review

AV Samrot, TC Sean, KS Bhavya, CS Sahithya… - Pathogens, 2021 - mdpi.com
Leptospirosis is a perplexing conundrum for many. In the existing literature, the
pathophysiological mechanisms pertaining to leptospirosis is still not understood in full …

Leptospira as an Emerging Pathogen: A Review of its Biology, Pathogenesis and Host Immune Responses

KV Evangelista, J Coburn - Future microbiology, 2010 - Taylor & Francis
Leptospirosis, the most widespread zoonosis in the world, is an emerging public health
problem, particularly in large urban centers of develo** countries. Several pathogenic …

Detection of pathogenic Leptospira spp. through TaqMan polymerase chain reaction targeting the LipL32 gene

RA Stoddard, JE Gee, PP Wilkins… - … and infectious disease, 2009 - Elsevier
Rapid diagnosis of leptospirosis, through culture and/or serology, can be difficult without
proper expertise and is often delayed because of the length of time required to obtain …

Proteome-wide cellular protein concentrations of the human pathogen Leptospira interrogans

J Malmström, M Beck, A Schmidt, V Lange… - Nature, 2009 - nature.com
Mass-spectrometry-based methods for relative proteome quantification have broadly
affected life science research. However, important research directions, particularly those …

Genome Sequence of the Saprophyte Leptospira biflexa Provides Insights into the Evolution of Leptospira and the Pathogenesis of Leptospirosis

M Picardeau, DM Bulach, C Bouchier, RL Zuerner… - PloS one, 2008 - journals.plos.org
Leptospira biflexa is a free-living saprophytic spirochete present in aquatic environments.
We determined the genome sequence of L. biflexa, making it the first saprophytic Leptospira …

Genome reduction in Leptospira borgpetersenii reflects limited transmission potential

DM Bulach, RL Zuerner, P Wilson, T Seemann… - Proceedings of the …, 2006 - pnas.org
Leptospirosis is one of the most common zoonotic diseases in the world, resulting in high
morbidity and mortality in humans and affecting global livestock production. Most infections …

Multilocus sequence ty** method for identification and genotypic classification of pathogenic Leptospira species

N Ahmed, SM Devi, M De los Á Valverde… - Annals of clinical …, 2006 - Springer
Background Leptospira are the parasitic bacterial organisms associated with a broad range
of mammalian hosts and are responsible for severe cases of human Leptospirosis. The …