Contributions of the early-life microbiome to childhood atopy and asthma development

H Steininger, J Moltzau-Anderson, SV Lynch - Seminars in immunology, 2023 - Elsevier
The rapid rise in atopy and asthma in industrialized nations has led to the identification of
early life environmental factors that promote these conditions and spurred research into how …

Emerging topical drug delivery approaches for the treatment of Atopic dermatitis

S Ghosalkar, P Singh… - Journal of Cosmetic …, 2022 - Wiley Online Library
Background Atopic dermatitis is a chronic, relapsing skin inflammation disease that
generally affects 20% of children and 1–3% of adults. It is characterized by pruritus …

From birth to overweight and atopic disease: multiple and common pathways of the infant gut microbiome

K Vu, W Lou, HM Tun, TB Konya, N Morales-Lizcano… - Gastroenterology, 2021 - Elsevier
Background & Aims Few studies, even those with cohort designs, test the mediating effects
of infant gut microbes and metabolites on the onset of disease. We undertook such a study …

Risk of adult‐onset asthma increases with the number of allergic multimorbidities and decreases with age

S Toppila‐Salmi, S Chanoine, J Karjalainen… - Allergy, 2019 - Wiley Online Library
Background The aim was to study the association between allergic multimorbidity and adult‐
onset asthma considering the number of allergic diseases and the age effect. Methods We …

Asthma prevalence among United States population insights from NHANES data analysis

S Swed, B Sawaf, F Al-Obeidat, W Hafez, A Rakab… - Scientific Reports, 2024 - nature.com
Asthma is a prevalent respiratory condition that poses a substantial burden on public health
in the United States. Understanding its prevalence and associated risk factors is vital for …

Outdoor Alternaria and Cladosporium spores and acute asthma

Y Olsen, E Arildskov, SN Hansen… - Clinical & …, 2023 - Wiley Online Library
Abstract Background Outdoor Alternaria and Cladosporium spores are ubiquitous. Few
studies have assessed their impact on asthma hospitalizations providing conflicting results …

Analysis of the predicting factors of recurrent wheezing in infants

J Zhai, Y Zou, J Liu, X **, C Ma, J Li, R Guo… - Italian Journal of …, 2019 - Springer
Background Clinically, asthma in children under 5 years old is under estimated because
lack of diagnostic criteria. The current study was, therefore, designed to identify the …

Exploring the Complexities of Atopic Dermatitis: Pathophysiological Mechanisms and Therapeutic Approaches

F Chaudhary, W Lee, T Escander… - … of biotechnology and …, 2024 - pmc.ncbi.nlm.nih.gov
Atopic dermatitis (AD) is a prevalent inflammatory skin condition impacting both children and
adults globally, with a prevalence of 15–30%. It ranks as the most prevalent skin disorder …

Obesity-related asthma in children is characterized by T-helper 1 rather than T-helper 2 immune response: A meta-analysis

TM Nyambuya, PV Dludla, V Mxinwa… - Annals of Allergy, Asthma …, 2020 - Elsevier
Background Asthma is a chronic inflammatory condition characterized by T-helper (TH) 2
polarization. In children, the prevalence of obesity is associated with an increased incidence …

Asthma: a loss of post-natal homeostatic control of airways smooth muscle with regression toward a pre-natal state

MB Anthracopoulos, ML Everard - Frontiers in Pediatrics, 2020 - frontiersin.org
The defining feature of asthma is loss of normal post-natal homeostatic control of airways
smooth muscle (ASM). This is the key feature that distinguishes asthma from all other forms …