The investigation of macromolecular biomolecules with ion mobility mass spectrometry (IM-
MS) techniques has provided substantial insights into the field of structural biology over the …

The annotation of small molecules remains a major challenge in untargeted mass
spectrometry-based metabolomics. We here critically discuss structured elucidation …

Improvements in the performance and availability of commercial instrumentation have made
ion mobility-mass spectrometry (IM-MS) an increasingly popular approach for the structural …

Cells encode information in the sequence of biopolymers, such as nucleic acids, proteins,
and glycans. Although glycans are essential to all living organisms, surprisingly little is …

Here we present an optimized workflow for global proteome and phosphoproteome analysis
of tissues or cell lines that uses isobaric tags (TMT (tandem mass tags)-10) for multiplexed …

Here we present a guide to ion mobility mass spectrometry experiments, which covers both
linear and nonlinear methods: what is measured, how the measurements are done, and how …

Researchers worldwide are taking advantage of novel, commercially available,
technologies, such as ion mobility mass spectrometry (IM‐MS), for metabolomics and …

In the last 2 decades, lipidomics has become one of the fastest expanding scientific
disciplines in biomedical research. With an increasing number of new research groups to …

The confident identification of metabolites and xenobiotics in biological and environmental
studies is an analytical challenge due to their immense dynamic range, vast chemical space …

Large numbers of cells are generally required for quantitative global proteome profiling due
to surface adsorption losses associated with sample processing. Such bulk measurement …