Cancer cells undergo metabolic reprogramming and switch to a 'glycolysis-
dominant'metabolic profile to promote their survival and meet their requirements for energy …

The Warburg effect, characterized by the preferential conversion of glucose to lactate even
in the presence of oxygen and functional mitochondria, is a prominent metabolic hallmark of …

Eukaryotic cells engage in autophagy, an internal process of self-degradation through
lysosomes. Autophagy can be classified as selective or non-selective depending on the way …

Autophagy is a conserved method of quality control in which cytoplasmic contents are
degraded via lysosomes. Lipophagy, a form of selective autophagy and a novel type of lipid …

Simple Summary Reprogramming of glucose metabolism is a hallmark of cancer and can be
targeted by therapeutic agents. Some metabolism regulators, such as ivosidenib and …

Glycolytic reprogramming is one of the most important features of cancer and plays an
integral role in the progression of cancer. In cancer cells, changes in glucose metabolism …

Lipids are essential constituents for malignant tumors, as they are absolutely required for
tumor growth and dissemination. Provided by the tumor microenvironment (TME) or by …

Lipid droplets (LDs) are cellular organelles comprising a core of neutral lipids (glycerides,
sterols) encased within a single phospholipid membrane, responsible for storing surplus …

Cancer reprogramming is an important facilitator of cancer development and survival, with
tumor cells exhibiting a preference for aerobic glycolysis beyond oxidative phosphorylation …

Background Chemotherapy resistance is a primary reason of ovarian cancer therapy failure;
hence it is important to investigate the underlying mechanisms of chemotherapy resistance …