Ocular drug delivery has constantly challenged ophthalmologists and drug delivery
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …

Novel biomaterials are becoming more crucial in treating human diseases. However, many
materials require complex artificial modifications and synthesis, leading to potential …

Cyclosporine is an immunomodulatory drug commonly used for the treatment of mild-to-
severe dry eye syndrome as well as intermediate and posterior segment diseases as uveitis …

Presently, different types of eye diseases, such as glaucoma, myopia, infection, and dry eyes
are treated with topical eye drops. However, due to ocular surface barriers, eye drops …

The eyes possess sophisticated physiological structures, diverse disease targets, limited
drug delivery space, distinctive barriers, and complicated biomechanical processes …

Ocular drug delivery and therapy systems have been extensively investigated with various
methods including direct injections, eye drops and contact lenses. Nowadays, smart contact …

Sufficient ocular bioavailability is often considered a challenge by the researchers, due to
the complex structure of the eye and its protective physiological mechanisms. In addition, the …

In recent years, nano-based drug delivery systems have gradually been regarded as a
promising approach to improve the current glioblastoma treatment, attracting many …

Intranasal drug delivery is as a noninvasive and efficient approach extensively utilized for
treating the local, central nervous system, and systemic diseases. Despite numerous …

Retinal ganglion cells (RGCs) are neurons of the visual system that are responsible for
transmitting signals from the retina to the brain via the optic nerve. Glaucoma is an optic …