Stimuli-responsive drug delivery systems triggered by intracellular or subcellular microenvironments
T Sun, C Jiang - Advanced Drug Delivery Reviews, 2023 - Elsevier
Drug delivery systems (DDS) triggered by local microenvironment represents the state-of-art
of nanomedicine design, where the triggering hallmarks at intracellular and subcellular …
of nanomedicine design, where the triggering hallmarks at intracellular and subcellular …
The aftermath of the interplay between the endoplasmic reticulum stress response and redox signaling
The endoplasmic reticulum (ER) is an essential organelle of eukaryotic cells. Its main
functions include protein synthesis, proper protein folding, protein modification, and the …
functions include protein synthesis, proper protein folding, protein modification, and the …
MitoCarta3. 0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations
The mammalian mitochondrial proteome is under dual genomic control, with 99% of proteins
encoded by the nuclear genome and 13 originating from the mitochondrial DNA (mtDNA) …
encoded by the nuclear genome and 13 originating from the mitochondrial DNA (mtDNA) …
[HTML][HTML] Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context
Mitochondria are key organelles for cellular energetics, metabolism, signaling, and quality
control and have been linked to various diseases. Different views exist on the composition of …
control and have been linked to various diseases. Different views exist on the composition of …
De novo birth of functional microproteins in the human lineage
Small open reading frames (sORFs) can encode functional" microproteins" that perform
crucial biological tasks. However, their size makes them less amenable to genomic analysis …
crucial biological tasks. However, their size makes them less amenable to genomic analysis …
The dark proteome: translation from noncanonical open reading frames
Omics-based technologies have revolutionized our understanding of the coding potential of
the genome. In particular, these studies revealed widespread unannotated open reading …
the genome. In particular, these studies revealed widespread unannotated open reading …
Mechanism of increased risk of insulin resistance in aging skeletal muscle
J Shou, PJ Chen, WH ** type 2 diabetes increases, which is associated with
senile skeletal muscle dysfunction. During skeletal muscle aging, mitochondrial dysfunction …
senile skeletal muscle dysfunction. During skeletal muscle aging, mitochondrial dysfunction …
Mitochondrial proteome research: the road ahead
Mitochondria are multifaceted organelles with key roles in anabolic and catabolic
metabolism, bioenergetics, cellular signalling and nutrient sensing, and programmed cell …
metabolism, bioenergetics, cellular signalling and nutrient sensing, and programmed cell …
Revisiting sORFs: overcoming challenges to identify and characterize functional microproteins
Short ORFs (sORFs), that is, occurrences of a start and stop codon within 100 codons or
less, can be found in organisms of all domains of life, outnumbering annotated protein …
less, can be found in organisms of all domains of life, outnumbering annotated protein …
Mitochondrial peptide BRAWNIN is essential for vertebrate respiratory complex III assembly
The emergence of small open reading frame (sORF)-encoded peptides (SEPs) is rapidly
expanding the known proteome at the lower end of the size distribution. Here, we show that …
expanding the known proteome at the lower end of the size distribution. Here, we show that …