The endoplasmic reticulum (ER) is an essential organelle of eukaryotic cells. Its main
functions include protein synthesis, proper protein folding, protein modification, and the …

The endoplasmic reticulum is an important intracellular organelle that plays an important
role in maintaining cellular homeostasis. Endoplasmic reticulum stress (ERS) and unfolded …

Endoplasmic reticulum (ER) stress is easily observed in chronic liver disease, which often
causes accumulation of unfolded or misfolded proteins in the ER, leading to unfolded …

Hepatitis B virus (HBV) infection is a major global health problem causing acute and chronic
liver disease that can lead to liver cirrhosis and hepatocellular carcinoma (HCC). HBV …

Viruses are intracellular parasites that subvert the functions of their host cells to accomplish
their infection cycle. The endoplasmic reticulum (ER)-residing chaperone proteins are …

About 250 million people worldwide are chronically infected with Hepatitis B virus (HBV),
contributing to a large burden on public health. Despite the existence of vaccines and …

Polymethoxyflavanoids (PMFs) have exhibited a vast array of therapeutic biological
properties. 5-O-Demethylnobiletin (5-DN) is one such PMF having anti-inflammatory activity …

Endoplasmic reticulum (ER) is the largest membrane-bound compartment in all cells and
functions as a key regulator in protein biosynthesis, lipid metabolism, and calcium balance …

In diverse viral infections, the production of excess viral particles containing only viral
glycoproteins (subviral particles or SVP) is commonly observed and is a commonly evolved …

The immunopathogenesis and molecular mechanisms involved during a hepatitis B virus
(HBV) infection have made the approaches for research complex, especially concerning the …