[HTML][HTML] Ethical and safety issues of stem cell-based therapy

V Volarevic, BS Markovic, M Gazdic… - … journal of medical …, 2018 - ncbi.nlm.nih.gov
Results obtained from completed and on-going clinical studies indicate huge therapeutic
potential of stem cell-based therapy in the treatment of degenerative, autoimmune and …

Emerging trends in regenerative medicine: a scientometric analysis in CiteSpace

C Chen, Z Hu, S Liu, H Tseng - Expert opinion on biological …, 2012 - Taylor & Francis
Introduction: Regenerative medicine involves research in a number of fields and disciplines
such as stem cell research, tissue engineering and biological therapy in general. As …

Structural cells are key regulators of organ-specific immune responses

T Krausgruber, N Fortelny, V Fife-Gernedl… - Nature, 2020 - nature.com
The mammalian immune system implements a remarkably effective set of mechanisms for
fighting pathogens. Its main components are haematopoietic immune cells, including …

[HTML][HTML] Rapid single-step induction of functional neurons from human pluripotent stem cells

Y Zhang, CH Pak, Y Han, H Ahlenius, Z Zhang… - Neuron, 2013 - cell.com
Available methods for differentiating human embryonic stem cells (ESCs) and induced
pluripotent cells (iPSCs) into neurons are often cumbersome, slow, and variable …

lincRNAs act in the circuitry controlling pluripotency and differentiation

M Guttman, J Donaghey, BW Carey, M Garber… - Nature, 2011 - nature.com
Although thousands of large intergenic non-coding RNAs (lincRNAs) have been identified in
mammals, few have been functionally characterized, leading to debate about their biological …

Nephron organoids derived from human pluripotent stem cells model kidney development and injury

R Morizane, AQ Lam, BS Freedman, S Kishi… - Nature …, 2015 - nature.com
Kidney cells and tissues derived from human pluripotent stem cells (hPSCs) may enable
organ regeneration, disease modeling and drug screening. We report an efficient …

[BOOK][B] Principles of tissue engineering

R Lanza, R Langer, JP Vacanti, A Atala - 2020 - books.google.com
Now in its fifth edition, Principles of Tissue Engineering has been the definite resource in the
field of tissue engineering for more than a decade. The fifth edition provides an update on …

EBSeq: an empirical Bayes hierarchical model for inference in RNA-seq experiments

N Leng, JA Dawson, JA Thomson, V Ruotti… - …, 2013 - academic.oup.com
Motivation: Messenger RNA expression is important in normal development and
differentiation, as well as in manifestation of disease. RNA-seq experiments allow for the …

The promise of induced pluripotent stem cells in research and therapy

DA Robinton, GQ Daley - Nature, 2012 - nature.com
The field of stem-cell biology has been catapulted forward by the startling development of
reprogramming technology. The ability to restore pluripotency to somatic cells through the …

Precise correction of Duchenne muscular dystrophy exon deletion mutations by base and prime editing

F Chemello, AC Chai, H Li, C Rodriguez-Caycedo… - Science …, 2021 - science.org
Duchenne muscular dystrophy (DMD) is a fatal muscle disease caused by the lack of
dystrophin, which maintains muscle membrane integrity. We used an adenine base editor …