Clinical development and potential of photothermal and photodynamic therapies for cancer

X Li, JF Lovell, J Yoon, X Chen - Nature reviews Clinical oncology, 2020 - nature.com
Light-activated, photosensitizer-based therapies have been established as safe modalities
of tumour ablation for numerous cancer indications. Two main approaches are available …

[HTML][HTML] Porphyrin photosensitizers in photodynamic therapy and its applications

J Kou, D Dou, L Yang - Oncotarget, 2017 - ncbi.nlm.nih.gov
In 1841, the extraction of hematoporphyrin from dried blood by removing iron marked the
birth of the photosensitizer. The last twenty years has witnessed extensive research in the …

[HTML][HTML] Unleashing the power of porphyrin photosensitizers: Illuminating breakthroughs in photodynamic therapy

A Akbar, S Khan, T Chatterjee, M Ghosh - Journal of Photochemistry and …, 2023 - Elsevier
This comprehensive review provides the current trends and recent developments of
porphyrin-based photosensitizers. We discuss their evolution from first-generation to third …

Photodynamic therapy of cancer: an update

P Agostinis, K Berg, KA Cengel… - CA: a cancer journal …, 2011 - Wiley Online Library
Photodynamic therapy (PDT) is a clinically approved, minimally invasive therapeutic
procedure that can exert a selective cytotoxic activity toward malignant cells. The procedure …

Photodynamic therapy for the treatment of glioblastoma

SW Cramer, CC Chen - Frontiers in Surgery, 2020 - frontiersin.org
Glioblastoma is the most common form of adult brain cancer and remains one of the
deadliest of human cancers. The current standard-of-care involves maximal tumor resection …

Photodynamic therapy for cancer: Role of natural products

B Mansoori, A Mohammadi, MA Doustvandi… - Photodiagnosis and …, 2019 - Elsevier
Photodynamic therapy (PDT) is a promising modality for the treatment of cancer. PDT
involves administering a photosensitizing dye, ie. photosensitizer, that selectively …

5‐ALA in the management of malignant glioma

H Stepp, W Stummer - Lasers in surgery and medicine, 2018 - Wiley Online Library
Background Patients suffering from malignant gliomas have a poor prognosis. For the
surgical treatment of these tumors, 5‐aminolevulinic acid (5‐ALA) has become a new …

Progress in clinical trials of photodynamic therapy for solid tumors and the role of nanomedicine

HO Alsaab, MS Alghamdi, AS Alotaibi, R Alzhrani… - Cancers, 2020 - mdpi.com
Simple Summary Photodynamic therapy (PDT) has been undertaken with growing focus in
recent studies to identify successful anticancer therapies. The field of PDT has evolved …

Drug carrier for photodynamic cancer therapy

TA Debele, S Peng, HC Tsai - International journal of molecular sciences, 2015 - mdpi.com
Photodynamic therapy (PDT) is a non-invasive combinatorial therapeutic modality using
light, photosensitizer (PS), and oxygen used for the treatment of cancer and other diseases …

Vascular targeted nanoparticles for imaging and treatment of brain tumors

GR Reddy, MS Bhojani, P McConville, J Moody… - Clinical Cancer …, 2006 - AACR
Purpose: Development of new therapeutic drug delivery systems is an area of significant
research interest. The ability to directly target a therapeutic agent to a tumor site would …