Impact of non-invasive biomarkers on hepatology practice: past, present and future

QM Anstee, L Castera, R Loomba - Journal of hepatology, 2022 - Elsevier
Over the last two decades, there have been tremendous advances in the non-invasive
diagnosis and risk stratification of chronic liver diseases (CLDs). Non-invasive approaches …

[HTML][HTML] Limitations of non-invasive tests for assessment of liver fibrosis

K Patel, G Sebastiani - JHEP Reports, 2020 - Elsevier
The diagnostic assessment of liver injury is an important step in the management of patients
with chronic liver disease (CLD). Although liver biopsy is the reference standard for the …

Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD): explanation and elaboration

KGM Moons, DG Altman, JB Reitsma… - Annals of internal …, 2015 - acpjournals.org
The TRIPOD (Transparent Reporting of a multivariable prediction model for Individual
Prognosis Or Diagnosis) Statement includes a 22-item checklist, which aims to improve the …

Clinical outcomes in patients with chronic hepatitis C after direct-acting antiviral treatment: a prospective cohort study

F Carrat, H Fontaine, C Dorival, M Simony, C Hezode… - The Lancet, 2019 - thelancet.com
Background Although direct-acting antivirals have been used extensively to treat patients
with chronic hepatitis C virus (HCV) infection, their clinical effectiveness has not been well …

[PDF][PDF] FIB‐4: an inexpensive and accurate marker of fibrosis in HCV infection. comparison with liver biopsy and fibrotest

A Vallet‐Pichard, V Mallet, B Nalpas, V Verkarre… - …, 2007 - Wiley Online Library
To optimize the management of patients with chronic hepatitis C virus (HCV) infection,
noninvasive tests to determine the degree of hepatic fibrosis have been developed. The …

AASLD Practice Guideline on imaging-based noninvasive liver disease assessment of hepatic fibrosis and steatosis

RK Sterling, A Duarte-Rojo, K Patel, SK Asrani… - Hepatology, 2025 - journals.lww.com
Chronic liver disease (CLD) is associated with approximately two million annual deaths
worldwide and is an enormous health burden.[1, 2] The majority of liver-related outcomes …

[HTML][HTML] EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis

European Association for the Study of the Liver - Journal of hepatology, 2015 - Elsevier
Liver fibrosis is part of the structural and functional alterations in most chronic liver diseases.
It is one of the main prognostic factors as the amount of fibrosis is correlated with the risk of …

Noninvasive methods to assess liver disease in patients with hepatitis B or C

L Castera - Gastroenterology, 2012 - Elsevier
The prognosis and management of patients with chronic viral hepatitis B and C depend on
the amount and progression of liver fibrosis and the risk for cirrhosis. Liver biopsy …

Diagnostic accuracy and prognostic significance of blood fibrosis tests and liver stiffness measurement by FibroScan in non-alcoholic fatty liver disease

J Boursier, J Vergniol, A Guillet, JB Hiriart, A Lannes… - Journal of …, 2016 - Elsevier
Background & Aims NAFLD is highly prevalent but only a small subset of patients develop
advanced liver fibrosis with impaired liver-related prognosis. We aimed to compare blood …

[HTML][HTML] Non-invasive diagnosis of liver fibrosis and cirrhosis

Y Lurie, M Webb, R Cytter-Kuint… - World journal of …, 2015 - ncbi.nlm.nih.gov
The evaluation and follow up of liver fibrosis and cirrhosis have been traditionally performed
by liver biopsy. However, during the last 20 years, it has become evident that this “gold …