Pulmonary fibrosis and COVID-19: the potential role for antifibrotic therapy
In December, 2019, reports emerged from Wuhan, China, of a severe acute respiratory
disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). By the …
disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). By the …
[HTML][HTML] The therapeutic potential of galectin-3 inhibition in fibrotic disease
RJ Slack, R Mills, AC Mackinnon - … Journal of Biochemistry & Cell Biology, 2021 - Elsevier
Galectin-3 is a beta-galactoside-binding mammalian lectin and part of the 15 member
galectin family that are evolutionarily highly conserved. It is the only chimeric protein with a …
galectin family that are evolutionarily highly conserved. It is the only chimeric protein with a …
Plasma markers of disrupted gut permeability in severe COVID-19 patients
A disruption of the crosstalk between the gut and the lung has been implicated as a driver of
severity during respiratory-related diseases. Lung injury causes systemic inflammation …
severity during respiratory-related diseases. Lung injury causes systemic inflammation …
Hyperinflammation and fibrosis in severe COVID-19 patients: galectin-3, a target molecule to consider
COVID-19 disease have become so far the most important sanitary crisis in the XXI century.
In light of the events, any clinical resource should be considered to alleviate this crisis …
In light of the events, any clinical resource should be considered to alleviate this crisis …
Galectin-3 is required for the microglia-mediated brain inflammation in a model of Huntington's disease
Huntington's disease (HD) is a neurodegenerative disorder that manifests with movement
dysfunction. The expression of mutant Huntingtin (mHTT) disrupts the functions of brain …
dysfunction. The expression of mutant Huntingtin (mHTT) disrupts the functions of brain …
[HTML][HTML] The role of galectins in virus infection-A systemic literature review
WH Wang, CY Lin, MR Chang, AN Urbina… - Journal of Microbiology …, 2020 - Elsevier
Abstract Background Galectins are β-Galactose binding lectins expressed in numerous cells
and play multiple roles in various physiological and cellular functions. However, few …
and play multiple roles in various physiological and cellular functions. However, few …
Quercetin attenuates atherosclerotic inflammation by inhibiting galectin‐3‐NLRP3 signaling pathway
H Li, L **ao, H He, H Zeng, J Liu… - Molecular nutrition & …, 2021 - Wiley Online Library
Scope Atherosclerosis is the underlying pathogenesis of cardiovascular events caused by
inflammation, and dietary intervention has been recommended as one fundamental …
inflammation, and dietary intervention has been recommended as one fundamental …
Galectin‐3 is a potential mediator for atherosclerosis
Z Gao, Z Liu, R Wang, Y Zheng, H Li… - Journal of immunology …, 2020 - Wiley Online Library
Atherosclerosis is a multifactorial chronic inflammatory arterial disease forming the
pathological basis of many cardiovascular diseases such as coronary heart disease, heart …
pathological basis of many cardiovascular diseases such as coronary heart disease, heart …
[HTML][HTML] Immunopathology of galectin-3: an increasingly promising target in COVID-19
The pandemic brought on by the outbreak of severe acute respiratory syndrome coronavirus
2 (SARS-CoV2) has become a global health crisis, with over 22 million confirmed cases and …
2 (SARS-CoV2) has become a global health crisis, with over 22 million confirmed cases and …
COVID-19 as a Risk Factor for Alzheimer's Disease
Severe acute respiratory disease coronavirus 2 (SARS-CoV-2) is responsible for the
coronavirus disease 2019 (COVID-19) pandemic. Although a primarily respiratory disease …
coronavirus disease 2019 (COVID-19) pandemic. Although a primarily respiratory disease …