Understanding health inequalities through the lens of social epigenetics

CL Martin, L Ghastine, EK Lodge… - Annual review of …, 2022 - annualreviews.org
Longstanding racial/ethnic inequalities in morbidity and mortality persist in the United States.
Although the determinants of health inequalities are complex, social and structural factors …

Vitamin D and COVID‐19: role of ACE2, age, gender, and ethnicity

B Getachew, Y Tizabi - Journal of medical virology, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2) virus, disproportionally targets older people …

[HTML][HTML] Epigenetics, microRNA and metabolic syndrome: a comprehensive review

F Ramzan, MH Vickers, RF Mithen - International Journal of Molecular …, 2021 - mdpi.com
Epigenetics refers to the DNA chemistry changes that result in the modification of gene
transcription and translation independently of the underlying DNA coding sequence …

DNA methylation: a potential mediator between air pollution and metabolic syndrome

P Poursafa, Z Kamali, E Fraszczyk, HM Boezen… - Clinical …, 2022 - Springer
Given the global increase in air pollution and its crucial role in human health, as well as the
steep rise in prevalence of metabolic syndrome (MetS), a better understanding of the …

A critical theoretical approach to cancer disparities: breast cancer and the social determinants of health

S Gehlert, D Hudson, T Sacks - Frontiers in public health, 2021 - frontiersin.org
Breast cancer is the most commonly experienced cancer among women. Its high rates of
incidence and survival mean that a number of women will live it for periods of their lifetimes …

Ten years of EWAS

S Wei, J Tao, J Xu, X Chen, Z Wang, N Zhang… - Advanced …, 2021 - Wiley Online Library
Epigenome‐wide association study (EWAS) has been applied to analyze DNA methylation
variation in complex diseases for a decade, and epigenome as a research target has …

Genetics and epigenetics in obesity: what do we know so far?

M Keller, SIA Svensson, K Rohde-Zimmermann… - Current Obesity …, 2023 - Springer
Abstract Purpose of Review Enormous progress has been made in understanding the
genetic architecture of obesity and the correlation of epigenetic marks with obesity and …

Childhood trauma, the stress response and metabolic syndrome: a focus on DNA methylation

JS Womersley, J Nothling, S Toikumo… - European Journal of …, 2022 - Wiley Online Library
Childhood trauma (CT) is well established as a potent risk factor for the development of
mental disorders. However, the potential of adverse early experiences to exert chronic and …

Obesity-related epigenetic changes after bariatric surgery

AG Izquierdo, AB Crujeiras - Frontiers in endocrinology, 2019 - frontiersin.org
Objective: In recent years, an increasing number of studies have begun focusing on
epigenetics as a link between environmental factors and a greater predisposition to the …

Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci

CE Breeze, A Batorsky, MK Lee, MD Szeto, X Xu… - Genome medicine, 2021 - Springer
Background DNA methylation (DNAm) is associated with gene regulation and estimated
glomerular filtration rate (eGFR), a measure of kidney function. Decreased eGFR is more …