The blood–brain barrier (BBB) has a significant contribution to homeostasis and protection
of the CNS. However, it also limits the crossing of therapeutics and thereby complicates the …

Simple Summary Glioblastoma (GBM) is the most common form of primary malignant brain
tumor with a devastatingly poor prognosis. Tumor heterogeneity (cellular, molecular and …

The development of paclitaxel-loaded polymeric nanoparticles for the treatment of brain
tumors was investigated. Poly (lactide-glycolide)(PLGA) nanoparticles containing 10% w/w …

The clinical translation of new nanoparticle-based therapies for high-grade glioma (HGG)
remains extremely poor. This has partly been due to the lack of suitable preclinical mouse …

Nanotechnology is the process of modulating shape and size at the nanoscale to design
and manufacture structures, devices, and systems. Nanotechnology's prospective …

Progress in nanomedicine has enabled the development of smart hybrid nanostructures
(HNSs) for brain cancer theranostics, a novel platform that can diagnose the brain while …

Purpose. The goal of these studies was to provide proof of concept for a novel targeted
therapy for Glioblastoma Multiforme (GBM). Methods. These studies involve the evaluation …

Clinical outcomes for many childhood brain tumours remain poor, despite our increasing
understanding of the underlying disease biology. Advances in molecular diagnostics have …

Objective: Brain tumors are the most challenging of all tumors and accounts for about 3% of
all cancer allied deaths. The aim of the present review is to examine the brain tumor …

Background The most difficult kind of cancer to treat is brain cancer, which causes around
3% of all cancer-related deaths. The targeted delivery is improved with the use of …