In the context of the coronavirus disease 2019 (COVID-19) pandemic, the global healthcare
community has raced to find effective therapeutic agents against severe acute respiratory …

Over the last few years, there has been growing interest in measuring the contractile force
(CF) of engineered muscle tissues to evaluate their functionality. However, there are still no …

Skeletal muscle loss is a detrimental side-effect of numerous chronic diseases that
dramatically increases mortality and morbidity. The alteration of protein homeostasis is …

Tissue regeneration depends on the complex processes of angiogenesis, inflammation and
wound healing. Regarding muscle tissue, glucocorticoids (GCs) inhibit pro-inflammatory …

Stem cells are a unique class of cells that possess the ability to differentiate and self-renew,
enabling them to repair and replenish tissues. To protect and maintain the potential of stem …

Myotubes are mature muscle cells that form the basic structural element of skeletal muscle.
When stretching skeletal muscles, myotubes are subjected to passive tension as well. This …

The production of skeletal muscle constructs useful for replacing large defects in vivo, such
as in congenital diaphragmatic hernia (CDH), is still considered a challenge. The standard …

Engineering skeletal muscle tissue is crucial for the repair and replacement of damaged or
dysfunctional muscle. Despite numerous studies emphasizing the significance of skeletal …

Understanding the role of mechanical loading and exercise in skeletal muscle (SkM) is
paramount for delineating the molecular mechanisms that govern changes in muscle mass …

Targeted muscle reinnervation has been proposed for reconstruction of neuromuscular
function in amputees. However, it is unknown whether performing delayed targeted muscle …