Enterovirus A71 (EV-A71) infection has grown to become a serious threat to global public
health. It is one of the major causes of hand, foot, and mouth disease (HFMD) in infants and …

Picornaviruses constitute one of the most relevant viral groups according to their impact on
human and animal health. Etiologic agents of a broad spectrum of illnesses with a clinical …

Three mitochondrial metabolic pathways are required for efficient energy production in
eukaryotic cells: the electron transfer chain (ETC), fatty acid β-oxidation (FAO), and the …

Poliomyelitis is a highly infectious disease caused by poliovirus (PV). It can result in
paralysis and may be fatal. Integrated global immunization programs using live-attenuated …

Hepatitis E virus (HEV) is the causative agent of hepatitis E in humans and is the leading
cause of enterically transmitted viral hepatitis worldwide. Ribavirin (RBV) is currently the …

Hand, foot, and mouth disease (HFMD) is a highly contagious disease that usually affects
infants and young children (< 5 years). HFMD outbreaks occur frequently in the Asia-Pacific …

Enterovirus 71 (EV71) is a group of viruses that belongs to the Picornaviridae family, which
also includes viruses such as polioviruses. EV71, together with coxsackieviruses, is widely …

Enterovirus 71 (EV71) is the primary causative agent of hand, foot, and mouth disease
(HFMD). There is no effective drug therapy for EV71 at present. Small interfering RNA …

Abstract Echovirus 30 (E30), a serotype of Enterovirus B (EV-B), recently emerged as a
major causative agent of aseptic meningitis worldwide. E30 is particularly devastating in the …

Protective antibody levels are critical for protection from severe enterovirus 71 infection.
However, little is known about the specificities and functional properties of the enterovirus 71 …