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Lipid rafts: at a crossroad between cell biology and physics
K Jacobson, OG Mouritsen, RGW Anderson - Nature cell biology, 2007 - nature.com
Membrane lateral heterogeneity is accepted as a requirement for the function of biological
membranes and the notion of lipid rafts gives specificity to this broad concept. However, the …
membranes and the notion of lipid rafts gives specificity to this broad concept. However, the …
The structural role of cholesterol in cell membranes: from condensed bilayers to lipid rafts
MR Krause, SL Regen - Accounts of chemical research, 2014 - ACS Publications
Conspectus Defining the two-dimensional structure of cell membranes represents one of the
most daunting challenges currently facing chemists, biochemists, and biophysicists. In …
most daunting challenges currently facing chemists, biochemists, and biophysicists. In …
Higher-order transient membrane protein structures
This study shows that five membrane proteins—three GPCRs, an ion channel, and an
enzyme—form self-clusters under natural expression levels in a cardiac-derived cell line …
enzyme—form self-clusters under natural expression levels in a cardiac-derived cell line …
Membrane molecules mobile even after chemical fixation
To the Editor: Fixation of cells and tissues is the critical first step for histochemical or
cytochemical investigations1, 2. Recent efforts to visualize lipid rafts by immunofluorescence …
cytochemical investigations1, 2. Recent efforts to visualize lipid rafts by immunofluorescence …
Role of lipid rafts in pathogen-host interaction-a mini review
Lipid rafts, also known as microdomains, are important components of cell membranes and
are enriched in cholesterol, glycophospholipids and receptors. They are involved in various …
are enriched in cholesterol, glycophospholipids and receptors. They are involved in various …
Lipid rafts, cholesterol, and the brain
Lipid rafts are specialized membrane microdomains that serve as organizing centers for
assembly of signaling molecules, influence membrane fluidity and trafficking of membrane …
assembly of signaling molecules, influence membrane fluidity and trafficking of membrane …
Functional nanoscale organization of signaling molecules downstream of the T cell antigen receptor
Receptor-regulated cellular signaling often is mediated by formation of transient,
heterogeneous protein complexes of undefined structure. We used single and two-color …
heterogeneous protein complexes of undefined structure. We used single and two-color …
Correlation functions quantify super-resolution images and estimate apparent clustering due to over-counting
We present an analytical method using correlation functions to quantify clustering in super-
resolution fluorescence localization images and electron microscopy images of static …
resolution fluorescence localization images and electron microscopy images of static …
Plasma membrane-associated proteins are clustered into islands attached to the cytoskeleton
BF Lillemeier, JR Pfeiffer, Z Surviladze… - Proceedings of the …, 2006 - pnas.org
Although much evidence suggests that the plasma membrane of eukaryotic cells is not
homogenous, the precise architecture of this important structure has not been clear. Here we …
homogenous, the precise architecture of this important structure has not been clear. Here we …
Association of γ-secretase with lipid rafts in post-Golgi and endosome membranes
Alzheimer's disease-associated β-amyloid peptides (Aβ) are generated by the sequential
proteolytic processing of amyloid precursor protein (APP) by β-and γ-secretases. There is …
proteolytic processing of amyloid precursor protein (APP) by β-and γ-secretases. There is …