Vicious cycle of oxidative stress and neuroinflammation in pathophysiology of chronic vascular encephalopathy

TR Dmytriv, KV Duve, KB Storey… - Frontiers in physiology, 2024 - frontiersin.org
Chronic vascular encephalopathy (CVE) is a frequent cause of vascular mild cognitive
impairment and dementia, which significantly worsens the quality of life, especially in the …

[HTML][HTML] The Alteration of Microglial Calcium Homeostasis in Central Nervous System Disorders: A Comprehensive Review

AR Hasan, F Tasnim, M Aktaruzzaman, MT Islam… - Neuroglia, 2024 - mdpi.com
Microglia, the unique and motile immune cells of the central nervous system (CNS), function
as a security guard in maintaining CNS homeostasis, primarily through calcium signaling …

[HTML][HTML] IUPHAR review: Drug Repurposing in Schizophrenia–An Updated Review of Clinical Trials

JK Zaki, J Tomasik, S Bahn - Pharmacological Research, 2025 - Elsevier
There is an urgent need for mechanistically novel and more efficacious treatments for
schizophrenia, especially those targeting negative and cognitive symptoms with a more …