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Type 2 diabetes
Summary 415 million people live with diabetes worldwide, and an estimated 193 million
people have undiagnosed diabetes. Type 2 diabetes accounts for more than 90% of patients …
people have undiagnosed diabetes. Type 2 diabetes accounts for more than 90% of patients …
The pharmacology and therapeutic applications of monoclonal antibodies
MS Castelli, P McGonigle… - Pharmacology research & …, 2019 - Wiley Online Library
Monoclonal antibodies (mAbs) have emerged as a major class of therapeutic agents on the
market. To date, approximately 80 mAbs have been granted marketing approval. In 2018, 12 …
market. To date, approximately 80 mAbs have been granted marketing approval. In 2018, 12 …
Adherence to diabetes medication: a systematic review
Aims To investigate the extent of and factors associated with adherence to Type 2 diabetes
medication. Methods The CINAHL, Embase, International Pharmaceutical Abstracts …
medication. Methods The CINAHL, Embase, International Pharmaceutical Abstracts …
Nonadherence with antipsychotic medication in schizophrenia: challenges and management strategies
PM Haddad, C Brain, J Scott - Patient related outcome measures, 2014 - Taylor & Francis
Nonadherence with medication occurs in all chronic medical disorders. It is a particular
challenge in schizophrenia due to the illness's association with social isolation, stigma, and …
challenge in schizophrenia due to the illness's association with social isolation, stigma, and …
Glucagon‐like peptide‐1 receptor agonists in type 2 diabetes treatment: are they all the same?
R Gentilella, V Pechtner, A Corcos… - … research and reviews, 2019 - Wiley Online Library
Summary Glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are an important class
of drugs with a well‐established efficacy and safety profile in patients with type 2 diabetes …
of drugs with a well‐established efficacy and safety profile in patients with type 2 diabetes …
Identification of barriers to insulin therapy and approaches to overcoming them
D Russell‐Jones, F Pouwer… - Diabetes, Obesity and …, 2018 - Wiley Online Library
Poor glycaemic control in type 2 diabetes (T2D) is a global problem despite the availability
of numerous glucose‐lowering therapies and clear guidelines for T2D management …
of numerous glucose‐lowering therapies and clear guidelines for T2D management …
Pharmacokinetic and pharmacodynamic properties of the novel basal insulin Fc (insulin efsitora alfa), an insulin fusion protein in development for once‐weekly dosing …
T Heise, J Chien, JM Beals, C Benson… - Diabetes, Obesity …, 2023 - Wiley Online Library
Aim To assess the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of
basal insulin Fc (BIF; LY3209590), a fusion protein combining a novel single‐chain insulin …
basal insulin Fc (BIF; LY3209590), a fusion protein combining a novel single‐chain insulin …
Safety and efficacy of once-weekly basal insulin Fc in people with type 2 diabetes previously treated with basal insulin: a multicentre, open-label, randomised, phase 2 …
Background The burden of daily basal insulins often causes hesitancy and delays in the
initiation of insulin therapy. Basal insulin Fc (BIF, insulin efsitora alfa), designed for once …
initiation of insulin therapy. Basal insulin Fc (BIF, insulin efsitora alfa), designed for once …
[HTML][HTML] Clinical inertia and its impact on treatment intensification in people with type 2 diabetes mellitus
G Reach, V Pechtner, R Gentilella, A Corcos… - Diabetes & …, 2017 - Elsevier
Many people with type 2 diabetes mellitus (T2DM) fail to achieve glycaemic control promptly
after diagnosis and do not receive timely treatment intensification. This may be in part due to …
after diagnosis and do not receive timely treatment intensification. This may be in part due to …
[HTML][HTML] Clinical inertia to insulin initiation and intensification in the UK: a focused literature review
K Khunti, D Millar-Jones - Primary care diabetes, 2017 - Elsevier
Achieving tight glycaemic control early following the diagnosis of type 2 diabetes is key to
optimising clinical outcomes, yet many patients and clinicians are reluctant to initiate and …
optimising clinical outcomes, yet many patients and clinicians are reluctant to initiate and …