Thirty Years of (TMS)3SiH: A Milestone in Radical-Based Synthetic Chemistry

C Chatgilialoglu, C Ferreri, Y Landais… - Chemical …, 2018 - ACS Publications
This review is an update on tris (trimethylsilyl) silane, TTMSS, in organic chemistry, focusing
on the advancements of the past decade. The overview includes a wide range of chemical …

Recent progress in the synthesis and chemistry of azetidinones

GS Singh - Tetrahedron, 2003 - Elsevier
Natural and synthetic azetidinone derivatives occupy a central place among medicinally
important compounds due to their diverse and interesting antibiotic activities. 1–9 Even …

The mechanism of the ketene− imine (Staudinger) reaction in its centennial: still an unsolved problem?

FP Cossio, A Arrieta, MA Sierra - Accounts of chemical research, 2008 - ACS Publications
Although Staudinger reported the reaction between ketenes and imines 100 years ago
(1907), this process is still the most general and useful method for the synthesis of β-lactams …

Tin hydride substitutes in reductive radical chain reactions

A Studer, S Amrein - Synthesis, 2002 - thieme-connect.com
The substitution of a functional group for a hydrogen atom is a very important transformation
in synthetic organic chemistry. Reactions such as deoxygenations, deselenations …

Explorations on the total synthesis of the unusual marine alkaloid chartelline A

C Sun, X Lin, SM Weinreb - The Journal of Organic Chemistry, 2006 - ACS Publications
In work directed toward a total synthesis of chartelline A (1a), a strategy was investigated to
construct the 10-membered ring of this marine alkaloid via an intramolecular aldehyde/β …

Efficient one-pot synthesis of 2-azetidinones from acetic acid derivatives and imines using methoxymethylene-N, N-dimethyliminium salt

A Jarrahpour, M Zarei - Tetrahedron, 2010 - Elsevier
A cheap, versatile and convenient method for synthesis of β-lactams using
methoxymethylene-N, N-dimethyliminium salt as an acid activator in Staudinger reaction is …

Novel and recent synthesis and applications of β-lactams

L Troisi, C Granito, E Pindinelli - Heterocyclic Scaffolds I: ß-Lactams, 2010 - Springer
In this chapter, a comprehensive overview of the most significant and interesting
contributions published from 2000 until now, concerning the preparation of novel β-lactam …

Spirocyclic β-lactams: synthesis and biological evaluation of novel heterocycles

SS Bari, A Bhalla - Heterocyclic Scaffolds I: ß-Lactams, 2010 - Springer
Abstract β-Lactam rings containing compounds are a group of antibiotics of unparalleled
importance in chemotherapy. Considerable effort has been reported in the development of …

Synthesis and characterization of β-lactam functionalized superparamagnetic Fe 3 O 4@ SiO 2 nanoparticles as an approach for improvement of antibacterial activity …

M Esmaeilpour, AR Sardarian, A Jarrahpour… - RSC Advances, 2016 - pubs.rsc.org
In this paper, we reported, for the first time, a new multistep method for preparing β-lactam
functionalized Fe3O4@ SiO2 nanoparticles with high saturation magnetization. The …

Forging structural complexity: diastereoselective synthesis of densely substituted β-lactams with dual functional handles for enhanced core modifications

AMR Treviño, P Loch-Temzelides, S Pandiri… - Chemical …, 2024 - pubs.rsc.org
The preparation of the β-lactam motif containing both C–Br and N–O bonds as functional
handles remains an unmet synthetic challenge. Described herein is a novel and highly …