Parahydrogen‐based hyperpolarization for biomedicine

JB Hövener, AN Pravdivtsev, B Kidd… - Angewandte Chemie …, 2018 - Wiley Online Library
Magnetic resonance (MR) is one of the most versatile and useful physical effects used for
human imaging, chemical analysis, and the elucidation of molecular structures. However, its …

SABRE: Chemical kinetics and spin dynamics of the formation of hyperpolarization

DA Barskiy, S Knecht, AV Yurkovskaya… - Progress in Nuclear …, 2019 - Elsevier
In this review, we present the physical principles of the SABRE (Signal Amplification By
Reversible Exchange) method. SABRE is a promising hyperpolarization technique that …

Signal amplification by reversible exchange (SABRE): From discovery to diagnosis

PJ Rayner, SB Duckett - Angewandte Chemie International …, 2018 - Wiley Online Library
Signal amplification by reversible exchange (SABRE) turns typically weak magnetic
resonance responses into strong signals making previously impractical measurements …

Generalizing, extending, and maximizing nitrogen-15 hyperpolarization induced by parahydrogen in reversible exchange

JFP Colell, AWJ Logan, Z Zhou… - The Journal of …, 2017 - ACS Publications
Signal Amplification by Reversible Exchange (SABRE) is a fast and convenient NMR
hyperpolarization method that uses cheap and readily available para-hydrogen as a …

Over 20% 15N Hyperpolarization in Under One Minute for Metronidazole, an Antibiotic and Hypoxia Probe

DA Barskiy, RV Shchepin, AM Coffey… - Journal of the …, 2016 - ACS Publications
Direct NMR hyperpolarization of naturally abundant 15N sites in metronidazole is
demonstrated using SABRE-SHEATH (Signal Amplification by Reversible Exchange in …

Fine-tuning the efficiency of para-hydrogen-induced hyperpolarization by rational N-heterocyclic carbene design

PJ Rayner, P Norcott, KM Appleby, W Iali… - Nature …, 2018 - nature.com
Iridium N-heterocyclic carbene (NHC) complexes catalyse the para-hydrogen-induced
hyperpolarization process, Signal Amplification by Reversible Exchange (SABRE). This …

Parahydrogen-based NMR signal amplification by reversible exchange (SABRE): Recent advances and applications

OG Salnikov, DB Burueva, IV Skovpin… - Mendeleev …, 2023 - Elsevier
Signal amplification by reversible exchange (SABRE) is a rapidly develo** nuclear
magnetic resonance (NMR) hyperpolarization technique utilizing parahydrogen for dramatic …

A simple analytical model for signal amplification by reversible exchange (SABRE) process

DA Barskiy, AN Pravdivtsev, KL Ivanov… - Physical Chemistry …, 2016 - pubs.rsc.org
We demonstrate an analytical model for the description of the signal amplification by
reversible exchange (SABRE) process. The model relies on a combined analysis of …

[HTML][HTML] Perspectives for hyperpolarisation in compact NMR

ME Halse - TrAC Trends in Analytical Chemistry, 2016 - Elsevier
Nuclear magnetic resonance (NMR) is one of the most powerful analytical techniques
currently available, with applications in fields ranging from synthetic chemistry to clinical …

Direct hyperpolarization of nitrogen-15 in aqueous media with parahydrogen in reversible exchange

JFP Colell, M Emondts, AWJ Logan… - Journal of the …, 2017 - ACS Publications
Signal amplification by reversible exchange (SABRE) is an inexpensive, fast, and even
continuous hyperpolarization technique that uses para-hydrogen as hyperpolarization …