Rethinking mechanisms, diagnosis and management of endometriosis

C Chapron, L Marcellin, B Borghese… - Nature Reviews …, 2019 - nature.com
Endometriosis is a chronic inflammatory disease defined as the presence of endometrial
tissue outside the uterus, which causes pelvic pain and infertility. This disease should be …

Endometriosis‐associated infertility: aspects of pathophysiological mechanisms and treatment options

T Tanbo, P Fedorcsak - Acta obstetricia et gynecologica …, 2017 - Wiley Online Library
Endometriosis is a common condition in women of reproductive age. In addition to pain,
endometriosis may also reduce fertility. The causes of infertility in women with endometriosis …

Iron-overloaded follicular fluid increases the risk of endometriosis-related infertility by triggering granulosa cell ferroptosis and oocyte dysmaturity

Z Ni, Y Li, D Song, J Ding, S Mei, S Sun, W Cheng… - Cell death & …, 2022 - nature.com
Endometriosis (EMs) occurs in approximately 50% of women with infertility. The main
causes of EMs-related infertility are follicle dysplasia and reduced oocyte quality. Iron …

Chronic niche inflammation in endometriosis-associated infertility: current understanding and future therapeutic strategies

YH Lin, YH Chen, HY Chang, HK Au, CR Tzeng… - International journal of …, 2018 - mdpi.com
Endometriosis is an estrogen-dependent inflammatory disease that affects up to 10% of
women of reproductive age and accounts for up to 50% of female infertility cases. It has …

Impact of unilateral versus bilateral ovarian endometriotic cystectomy on ovarian reserve: a systematic review and meta-analysis

JS Younis, N Shapso, R Fleming… - Human reproduction …, 2018 - academic.oup.com
BACKGROUND Ovarian endometrioma is a frequent manifestation of endometriosis in
women of reproductive age. Several issues related to its space occupying effects, local …

Presence of adenomyosis at MRI reduces live birth rates in ART cycles for endometriosis

M Bourdon, P Santulli, C Bordonne… - Human …, 2022 - academic.oup.com
STUDY QUESTION What is the impact of adenomyosis on the live birth rate (LBR) in women
affected by endometriosis women undergoing ART? SUMMARY ANSWER For women …

Is dienogest the best medical treatment for ovarian endometriomas? Results of a multicentric case control study

S Angioni, A Pontis, ME Malune, V Cela… - Gynecological …, 2020 - Taylor & Francis
Ovarian endometriomas are common manifestations of endometriosis. Surgical excision has
been shown to potentially decrease ovarian reserves. In this prospective study, we included …

Prognostic factors for assisted reproductive technology in women with endometriosis-related infertility

C Maignien, P Santulli, V Gayet, MC Lafay-Pillet… - American journal of …, 2017 - Elsevier
Background Assisted reproductive technology is one of the therapeutic options offered for
managing endometriosis-associated infertility. Yet, published data on assisted reproductive …

Epigenetic factors in eutopic endometrium in women with endometriosis and infertility

M Adamczyk, E Wender-Ozegowska… - International Journal of …, 2022 - mdpi.com
Eutopic endometrium in patients with endometriosis is characterized by aberrant expression
of essential genes during the implantation window. It predisposes to disturbance of …

Identification of molecular subtypes and immune infiltration in endometriosis: a novel bioinformatics analysis and In vitro validation

S Lv, J Sun, L Gan, J Sun - Frontiers in Immunology, 2023 - frontiersin.org
Introduction Endometriosis is a worldwide gynacological diseases, affecting in 6–10% of
women of reproductive age. The aim of this study was to investigate the gene network and …