Liver metastases

DI Tsilimigras, P Brodt, PA Clavien… - Nature reviews Disease …, 2021 - nature.com
Liver metastases are commonly detected in a range of malignancies including colorectal
cancer (CRC), pancreatic cancer, melanoma, lung cancer and breast cancer, although CRC …

Augmenting anticancer immunity through combined targeting of angiogenic and PD-1/PD-L1 pathways: challenges and opportunities

SP Hack, AX Zhu, Y Wang - Frontiers in immunology, 2020 - frontiersin.org
Cancer immunotherapy (CIT) with antibodies targeting the programmed cell death 1 protein
(PD-1)/programmed cell death 1 ligand 1 (PD-L1) axis have changed the standard of care in …

[HTML][HTML] Lymph node colonization induces tumor-immune tolerance to promote distant metastasis

NE Reticker-Flynn, W Zhang, JA Belk, PA Basto… - Cell, 2022 - cell.com
For many solid malignancies, lymph node (LN) involvement represents a harbinger of
distant metastatic disease and, therefore, an important prognostic factor. Beyond its utility as …

[HTML][HTML] Patterns of metastasis in colon and rectal cancer

M Riihimäki, A Hemminki, J Sundquist, K Hemminki - Scientific reports, 2016 - nature.com
Investigating epidemiology of metastatic colon and rectal cancer is challenging, because
cancer registries seldom record metastatic sites. We used a population based approach to …

Epidemiology of liver metastases

SR Horn, KC Stoltzfus, EJ Lehrer, LA Dawson… - Cancer …, 2020 - Elsevier
Aims The objectives of this study were to (1) characterize the epidemiology of liver
metastases at the time of primary cancer diagnosis (synchronous liver metastases),(2) …

Organotropism: new insights into molecular mechanisms of breast cancer metastasis

W Chen, AD Hoffmann, H Liu, X Liu - NPJ precision oncology, 2018 - nature.com
Metastasis accounts for 90% of breast cancer mortality. Despite the significant progress
made over the past decade in cancer medicine our understanding of metastasis remains …

Molecular mechanisms of breast cancer metastasis to the lung: clinical and experimental perspectives

B Medeiros, AL Allan - International journal of molecular sciences, 2019 - mdpi.com
Breast cancer is the most commonly diagnosed cancer in women worldwide, and> 90% of
breast cancer-related deaths are associated with metastasis. Breast cancer spreads …

Metastatic sites and survival in lung cancer

M Riihimäki, A Hemminki, M Fallah, H Thomsen… - Lung cancer, 2014 - Elsevier
Objectives Population-based data on metastatic sites and survival in site-specific
metastases are lacking for lung cancer and for any cancer because most cancer registries …

Liver metastasis from colorectal cancer: pathogenetic development, immune landscape of the tumour microenvironment and therapeutic approaches

Y Wang, X Zhong, X He, Z Hu, H Huang, J Chen… - Journal of Experimental …, 2023 - Springer
Colorectal cancer liver metastasis (CRLM) is one of the leading causes of death among
patients with colorectal cancer (CRC). Although immunotherapy has demonstrated …

Metastatic spread in patients with gastric cancer

M Riihimäki, A Hemminki, K Sundquist… - …, 2016 - pmc.ncbi.nlm.nih.gov
Background The epidemiology of metastatic gastric cancer is unexplored because cancer
registries seldom cover metastatic involvement apart from “present or not”. We used a novel …