Mitochondrial impairment: A common motif in neuropsychiatric presentation? The link to the tryptophan–kynurenine metabolic system
M Tanaka, Á Szabó, E Spekker, H Polyák, F Tóth… - Cells, 2022 - mdpi.com
Nearly half a century has passed since the discovery of cytoplasmic inheritance of human
chloramphenicol resistance. The inheritance was then revealed to take place maternally by …
chloramphenicol resistance. The inheritance was then revealed to take place maternally by …
Manganese-induced neurotoxicity: new insights into the triad of protein misfolding, mitochondrial impairment, and neuroinflammation
Occupational or environmental exposure to manganese (Mn) can lead to the development of
“Manganism,” a neurological condition showing certain motor symptoms similar to …
“Manganism,” a neurological condition showing certain motor symptoms similar to …
A sexually dimorphic hypothalamic circuit controls maternal care and oxytocin secretion
It is commonly assumed, but has rarely been demonstrated,, that sex differences in
behaviour arise from sexual dimorphism in the underlying neural circuits,. Parental care is a …
behaviour arise from sexual dimorphism in the underlying neural circuits,. Parental care is a …
Silver nanoparticles reduce brain inflammation and related neurotoxicity through induction of H2S-synthesizing enzymes
Silver nanoparticles (AgNP) are known to penetrate into the brain and cause neuronal
death. However, there is a paucity in studies examining the effect of AgNP on the resident …
death. However, there is a paucity in studies examining the effect of AgNP on the resident …
Fyn kinase regulates microglial neuroinflammatory responses in cell culture and animal models of Parkinson's disease
Sustained neuroinflammation mediated by resident microglia is recognized as a key
pathophysiological contributor to many neurodegenerative diseases, including Parkinson's …
pathophysiological contributor to many neurodegenerative diseases, including Parkinson's …
Increased vulnerability of nigral dopamine neurons after expansion of their axonal arborization size through D2 dopamine receptor conditional knockout
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of
dopamine (DA) neurons in the substantia nigra pars compacta (SNc). Rare genetic …
dopamine (DA) neurons in the substantia nigra pars compacta (SNc). Rare genetic …
Organophosphate pesticide chlorpyrifos impairs STAT1 signaling to induce dopaminergic neurotoxicity: Implications for mitochondria mediated oxidative stress …
The organophosphate (OP) pesticide chlorpyrifos (CPF), used in agricultural settings,
induces developmental and neurological impairments. Recent studies using in vitro cell …
induces developmental and neurological impairments. Recent studies using in vitro cell …
Current understanding of methamphetamine-associated dopaminergic neurodegeneration and psychotoxic behaviors
EJ Shin, DK Dang, TV Tran, HQ Tran, JH Jeong… - Archives of Pharmacal …, 2017 - Springer
Clinical and preclinical studies have indicated that chronic methamphetamine (MA) use is
associated with extensive neurodegeneration, psychosis, and cognitive impairment …
associated with extensive neurodegeneration, psychosis, and cognitive impairment …
Role of mitochondria in methamphetamine-induced dopaminergic neurotoxicity: involvement in oxidative stress, neuroinflammation, and pro-apoptosis—a review
EJ Shin, HQ Tran, PT Nguyen, JH Jeong, SY Nah… - Neurochemical …, 2018 - Springer
Abstract Methamphetamine (MA), an amphetamine-type psychostimulant, is associated with
dopaminergic toxicity and has a high abuse potential. Numerous in vivo and in vitro studies …
dopaminergic toxicity and has a high abuse potential. Numerous in vivo and in vitro studies …
Ellagic acid protects dopamine neurons via inhibition of NLRP3 inflammasome activation in microglia
X He, Y Zhou, S Sheng, J Li, G Wang… - … Medicine and Cellular …, 2020 - Wiley Online Library
Neuroinflammation plays a crucial role in the pathological process of Parkinson's disease
(PD). Nod‐like receptor protein 3 (NLRP3) inflammasome was highly located in microglia …
(PD). Nod‐like receptor protein 3 (NLRP3) inflammasome was highly located in microglia …