[HTML][HTML] Regulation of inflammation by Interleukin-10 in the intestinal and respiratory mucosa
WJ Branchett, M Saraiva, A O'Garra - Current Opinion in Immunology, 2024 - Elsevier
Intricate immune regulation is required at mucosal surfaces to allow tolerance to microbiota
and harmless allergens and to prevent overexuberant inflammatory responses to …
and harmless allergens and to prevent overexuberant inflammatory responses to …
[HTML][HTML] Blimp-1 and c-Maf regulate immune gene networks to protect against distinct pathways of pathobiont-induced colitis
M Alvarez-Martinez, LS Cox, CF Pearson… - Nature …, 2024 - nature.com
Intestinal immune responses to microbes are controlled by the cytokine IL-10 to avoid
immune pathology. Here, we use single-cell RNA sequencing of colon lamina propria …
immune pathology. Here, we use single-cell RNA sequencing of colon lamina propria …
Identification of a transcription factor network regulating anti-TNF mediated IL10 expression in human CD4+ T cells
GAM Povoleri, ML Ridley, RJ Marrow… - Discovery …, 2024 - academic.oup.com
CD4+ T cells are key players in immune-mediated inflammatory diseases (IMIDs) through
the production of inflammatory mediators including tumour necrosis factor (TNF). Anti-TNF …
the production of inflammatory mediators including tumour necrosis factor (TNF). Anti-TNF …
Research briefing
WJ Branchett, A O'Garra - nature.com
The intestinal immune response is tightly controlled to limit inflammation, largely by the
cytokine IL-10, which prevents colitis. We report that the transcription factors c-MAF and …
cytokine IL-10, which prevents colitis. We report that the transcription factors c-MAF and …