Oxidative stress and neuroinflammation as a pivot in drug abuse. A focus on the therapeutic potential of antioxidant and anti-inflammatory agents and biomolecules

P Berríos-Cárcamo, M Quezada, ME Quintanilla… - Antioxidants, 2020 - mdpi.com
Drug abuse is a major global health and economic problem. However, there are no
pharmacological treatments to effectively reduce the compulsive use of most drugs of abuse …

The antero-posterior heterogeneity of the ventral tegmental area

MJ Sanchez-Catalan, J Kaufling, F Georges… - Neuroscience, 2014 - Elsevier
The ventral tegmental area (VTA) is a brain region processing salient sensory and emotional
information, controlling motivated behaviors, natural or drug-related reward, reward-related …

Mu opioid receptor modulation of dopamine neurons in the periaqueductal gray/dorsal raphe: a role in regulation of pain

C Li, JA Sugam, EG Lowery-Gionta… - …, 2016 - nature.com
The periaqueductal gray (PAG) is a brain region involved in nociception modulation, and an
important relay center for the descending nociceptive pathway through the rostral ventral …

Endogenous opiates and behavior: 2012

RJ Bodnar - Peptides, 2013 - Elsevier
This paper is the thirty-fifth consecutive installment of the annual review of research
concerning the endogenous opioid system. It summarizes papers published during 2012 …

Psychopharmacological interaction of alcohol and posttraumatic stress disorder: Effective action of naringin

B Ben-Azu, B Oritsemuelebi, AM Oghorodi… - European Journal of …, 2024 - Elsevier
Posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) are prevalently co-
occurring, important risk factors for a broad array of neuropsychiatric diseases. To date, how …

Salsolinol: an unintelligible and double-faced molecule—lessons learned from in vivo and in vitro experiments

M Kurnik-Łucka, P Panula, A Bugajski, K Gil - Neurotoxicity Research, 2018 - Springer
Abstract Salsolinol (1-methyl-6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline) is a
tetrahydroisoquinoline derivative whose presence in humans was first detected in the urine …

[HTML][HTML] Mood components in cocoa and chocolate: the mood pyramid

E Tuenter, K Foubert, L Pieters - Planta medica, 2018 - thieme-connect.com
Cocoa and chocolate, prepared from cocoa beans that originate from the fruits of the cocoa
tree Theobroma cacao, have a long-standing reputation as healthy food, including mood …

Alcohol-induced alterations in dopamine modulation of prefrontal activity

H Trantham-Davidson, LJ Chandler - Alcohol, 2015 - Elsevier
Long-term alcohol use leads to persistent cognitive deficits that may be associated with
maladaptive changes in the neurocircuitry that mediates executive functions. Impairments …

Mystic acetaldehyde: the never-ending story on alcoholism

AT Peana, MJ Sánchez-Catalán, L Hipólito… - Frontiers in Behavioral …, 2017 - frontiersin.org
After decades of uncertainties and drawbacks, the study on the role and significance of
acetaldehyde in the effects of ethanol seemed to have found its main paths. Accordingly, the …

Ethanol-dependent synthesis of salsolinol in the posterior ventral tegmental area as key mechanism of ethanol's action on mesolimbic dopamine

V Bassareo, R Frau, R Maccioni, P Caboni… - Frontiers in …, 2021 - frontiersin.org
Abnormal consumption of ethanol, the ingredient responsible for alcoholic drinks' addictive
liability, causes millions of deaths yearly. Ethanol's addictive potential is triggered through …