The emerging roles and potential applications of circular RNAs in ovarian cancer: a comprehensive review

S Najafi - Journal of Cancer Research and Clinical Oncology, 2023 - Springer
Ovarian cancer (OC) is among the most common human malignancies and the first cause of
deaths among gynecologic cancers. Early diagnosis can help improving prognosis in those …

[HTML][HTML] Critical roles of circular RNA in tumor metastasis via acting as a sponge of miRNA/isomiR

L Guo, L Jia, L Luo, X Xu, Y **ang, Y Ren… - International Journal of …, 2022 - mdpi.com
Circular RNAs (circRNAs), a class of new endogenous non-coding RNAs (ncRNAs), are
closely related to the carcinogenic process and play a critical role in tumor metastasis …

FL-circAS: an integrative resource and analysis for full-length sequences and alternative splicing of circular RNAs with nanopore sequencing

TW Chiang, SE Jhong, YC Chen, CY Chen… - Nucleic acids …, 2024 - academic.oup.com
Abstract Circular RNAs (circRNAs) are RNA molecules with a continuous loop structure
characterized by back-splice junctions (BSJs). While analyses of short-read RNA …

Circ_0007142 downregulates miR‐874‐3p‐mediated GDPD5 on colorectal cancer cells

Y Wang, H Chen, X Wei - European journal of clinical …, 2021 - Wiley Online Library
Background Ferroptosis is an iron‐dependent and oxidative cell death form. Recent studies
suggested that circular RNAs (circRNAs) regulated ferroptosis in tumour cells …

[HTML][HTML] The role of PKM2 in metabolic reprogramming: insights into the regulatory roles of non-coding RNAs

DL Puckett, M Alquraishi, W Chowanadisai… - International Journal of …, 2021 - mdpi.com
Pyruvate kinase is a key regulator in glycolysis through the conversion of
phosphoenolpyruvate (PEP) into pyruvate. Pyruvate kinase exists in various isoforms that …

An integrated electrochemical POCT platform for ultrasensitive circRNA detection towards hepatocellular carcinoma diagnosis

B Zhang, M Chen, J Cao, Y Liang, T Tu, J Hu… - Biosensors and …, 2021 - Elsevier
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related death. Circ-
CDYL, one of the circular RNAs (circRNAs), is recognized as an independent marker for …

[HTML][HTML] Role of circular RNAs and gut microbiome in gastrointestinal cancers and therapeutic targets

ST Abdullah, SR Abdullah, BM Hussen… - Non-coding RNA …, 2024 - Elsevier
Gastrointestinal cancers are a huge worldwide health concern, which includes a wide
variety of digestive tract cancers. Circular RNAs (circRNAs), a kind of non-coding RNA …

Sensitive, reliable and robust circRNA detection from RNA-seq with CirComPara2

E Gaffo, A Buratin, A Dal Molin… - Briefings in …, 2022 - academic.oup.com
Circular RNAs (circRNAs) are a large class of covalently closed RNA molecules originating
by a process called back-splicing. CircRNAs are emerging as functional RNAs involved in …

CircGLIS3 promotes high-grade glioma invasion via modulating ezrin phosphorylation

Y Li, J Chen, Z Chen, X Xu, J Weng, Y Zhang… - Frontiers in cell and …, 2021 - frontiersin.org
High-grade glioma is highly invasive and malignant, resistant to combined therapies, and
easy to relapse. A better understanding of circular RNA (circRNA) biological function in high …

The expanding regulatory mechanisms and cellular functions of long non-coding RNAs (lncRNAs) in neuroinflammation

S Tripathi, B Shree, S Mohapatra, Swati, A Basu… - Molecular …, 2021 - Springer
LncRNAs have emerged as important regulatory molecules in biological processes. They
serve as regulators of gene expression pathways through interactions with proteins, RNA …