The functional role of sulforaphane in intestinal inflammation: a review

LY Wei, JK Zhang, L Zheng, Y Chen - Food & function, 2022 - pubs.rsc.org
Intestinal inflammation represented by inflammatory bowel disease (IBD) has become a
global epidemic disease and the number of patients with IBD continues to increase. This …

Interplay of broccoli/broccoli sprout bioactives with gut microbiota in reducing inflammation in inflammatory bowel diseases

J Holman, M Hurd, PL Moses, GM Mawe… - The Journal of nutritional …, 2023 - Elsevier
Abstract Inflammatory Bowel Diseases (IBD) are chronic, reoccurring, and debilitating
conditions characterized by inflammation in the gastrointestinal tract, some of which can …

Interplay between cruciferous vegetables and the gut microbiome: a multi-omic approach

JA Bouranis, LM Beaver, D Jiang, J Choi, CP Wong… - Nutrients, 2022 - mdpi.com
Brassica vegetables contain a multitude of bioactive compounds that prevent and suppress
cancer and promote health. Evidence suggests that the gut microbiome may be essential in …

Plant sources, extraction techniques, analytical methods, bioactivity, and bioavailability of sulforaphane: A review

X Men, X Han, G Oh, JH Im, J Lim, GH Cho… - Food Science and …, 2024 - Springer
Sulforaphane (SFN) is an isothiocyanate commonly found in cruciferous vegetables. It is
formed via the enzymatic hydrolysis of glucoraphanin by myrosinase. SFN exerts various …

[HTML][HTML] Promotion of healthy aging through the nexus of gut microbiota and dietary phytochemicals

LM Beaver, PE Jamieson, CP Wong, M Hosseinikia… - Advances in …, 2025 - Elsevier
Aging is associated with the decline of tissue and cellular functions, which can promote the
development of age-related diseases like cancer, cardiovascular disease …

Sulforaphane ameliorates bisphenol A-induced hepatic lipid accumulation by inhibiting endoplasmic reticulum stress

L Hong, Y Xu, D Wang, Q Zhang, X Li, C **e, J Wu… - Scientific Reports, 2023 - nature.com
The aim of the present study was to investigate the role of endoplasmic reticulum (ER) stress
in bisphenol A (BPA)–induced hepatic lipid accumulation as well as the protective effects of …

[HTML][HTML] Beneficial effect of GABA-rich fermented milk whey on nervous system and intestinal microenvironment of aging mice induced by D-galactose

W He, H Song, Z Yang, S Zhao, J Min, Y Jiang - Microbiological Research, 2024 - Elsevier
This study aims to investigate the protective effect of a freeze-dried powder prepared from a
fermentation milk whey containing a high-yield GABA strain (FDH-GABA) against D …

[HTML][HTML] Sulforaphane modulates some stress parameters in TPT-exposed Cyprinus carpio in relation to liver metabolome

C Zhang, J Ma, B Wang, C Pu, K Chang, J Zhu… - Ecotoxicology and …, 2024 - Elsevier
This study aimed to investigate the protective effect of sulforaphane (SFN) on liver injury
induced by triphenyltin (TPT) in Cyprinus carpio (C. carpio). The fish (average weight of …

Metabolic fate of dietary glucosinolates and their metabolites: a role for the microbiome

JA Bouranis, LM Beaver, E Ho - Frontiers in Nutrition, 2021 - frontiersin.org
Robust evidence shows that phytochemicals from cruciferous vegetables, like broccoli, are
associated with numerous health benefits. The anti-cancer properties of these foods are …

Utilization of host and microbiome features in determination of biological aging

K Ratiner, SK Abdeen, K Goldenberg, E Elinav - Microorganisms, 2022 - mdpi.com
The term 'old age'generally refers to a period characterized by profound changes in human
physiological functions and susceptibility to disease that accompanies the final years of a …