This review covers article and patent data obtained mostly within the period 2013− 2023 on
the synthesis and biological activity of quinazolines [c]-annelated by five-and six-membered …

Bacterial infections cause substantial morbidity and mortality across the world and pose
serious threats to humankind. Drug resistance, especially multidrug resistance resulting from …

Magnetic Cu-MOF-74 (Fe3O4@ SiO2@ Cu-MOF-74) was synthesized for the first time by
grafting MOF-74 (copper as the metal center) on the surface of core-shell magnetic carboxyl …

Fourteen steroid compounds were in silico evaluated using computer program PASS as
antimicrobial agents. The experimental studies evaluation revealed that all compounds have …

Mechanisms for formation and hydrolysis of biologically active 2-substituted [1, 2, 4] triazolo
[1, 5-c] quinazolines were modeled at the SMD/B3LYP/6–31+ G (d) theory level. Obtained …

Quinazolines represent a class of nitrogen-containing heterocyclics with a broad spectrum of
biological applications. Many studies have explored the medicinal qualities of quinazoline …

In this study, starting from 1H‐1, 2, 4‐triazole, a new series of aliphatic ether derivatives
containing phenyl and 1H‐1, 2, 4‐triazole groups together were synthesized using reduction …

Eleven 3-amino-2-methyl-quinazolin-4 (3 H)-ones have been synthesized, in good to
excellent yields, via their corresponding benzoxazinones using an efficient tandem …

Triazoloquinazoline is a fused heterocyclic nucleus, formed by the fusion of two fundamental
heterocyclic moieties; triazole and quinazoline. This class of compound is known for its …

Abstract The derivatives of 1, 2, 4-triazole have attracted great attention among medicinal
chemists due to their wide range of biological activity, good pharmacodynamic and …