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The biological applications of DNA nanomaterials: current challenges and future directions
W Ma, Y Zhan, Y Zhang, C Mao, X **e… - Signal transduction and …, 2021 - nature.com
DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …
biological applications as driven by DNA nanotechnology in the past decades, including …
The basic properties of gold nanoparticles and their applications in tumor diagnosis and treatment
X Bai, Y Wang, Z Song, Y Feng, Y Chen… - International journal of …, 2020 - mdpi.com
Gold nanoparticles (AuNPs) have been widely studied and applied in the field of tumor
diagnosis and treatment because of their special fundamental properties. In order to make …
diagnosis and treatment because of their special fundamental properties. In order to make …
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy
The reactive oxygen species (ROS)-mediated mechanism is the major cause underlying the
efficacy of photodynamic therapy (PDT). The PDT procedure is based on the cascade of …
efficacy of photodynamic therapy (PDT). The PDT procedure is based on the cascade of …
Aptamer-based targeted therapy
Precision medicine holds great promise to harness genetic and epigenetic cues for targeted
treatment of a variety of diseases, ranging from many types of cancers, neurodegenerative …
treatment of a variety of diseases, ranging from many types of cancers, neurodegenerative …
Isothermal amplification of nucleic acids
Isothermal amplification of nucleic acids is a simple process that rapidly and efficiently
accumulates nucleic acid sequences at constant temperature. Since the early 1990s …
accumulates nucleic acid sequences at constant temperature. Since the early 1990s …
Self-assembling nucleic acid nanostructures functionalized with aptamers
Researchers have worked for many decades to master the rules of biomolecular design that
would allow artificial biopolymer complexes to self-assemble and function similarly to the …
would allow artificial biopolymer complexes to self-assemble and function similarly to the …
Cancer diagnosis with DNA molecular computation
C Zhang, Y Zhao, X Xu, R Xu, H Li, X Teng, Y Du… - Nature …, 2020 - nature.com
Early and precise cancer diagnosis substantially improves patient survival. Recent work has
revealed that the levels of multiple microRNAs in serum are informative as biomarkers for …
revealed that the levels of multiple microRNAs in serum are informative as biomarkers for …
Aptamer-integrated DNA nanostructures for biosensing, bioimaging and cancer therapy
The combination of nanostructures with biomolecules leading to the generation of functional
nanosystems holds great promise for biotechnological and biomedical applications. As a …
nanosystems holds great promise for biotechnological and biomedical applications. As a …
Construction of a multiple-aptamer-based DNA logic device on live cell membranes via associative toehold activation for accurate cancer cell identification
The ability to accurately identify and isolate cells is the cornerstone of precise disease
diagnosis and therapies. A single-step cell identification method based on logic analysis of …
diagnosis and therapies. A single-step cell identification method based on logic analysis of …
DNA-based dynamic mimicry of membrane proteins for programming adaptive cellular interactions
J Li, K Xun, L Zheng, X Peng, L Qiu… - Journal of the American …, 2021 - ACS Publications
Cells sense and respond to the external environment, mainly through proteins presented on
the membrane where their expression and conformation are dynamically regulated via …
the membrane where their expression and conformation are dynamically regulated via …