Therapeutic potential of cannabinoids in glaucoma

T Lindner, D Schmidl, L Peschorn, V Pai… - Pharmaceuticals, 2023 - mdpi.com
Glaucoma is a leading cause of irreversible blindness worldwide. To date, intraocular
pressure (IOP) is the only modifiable risk factor in glaucoma treatment, but even in treated …

Diet, oxidative stress, and blood serum nutrients in various types of glaucoma: a systematic review

M Młynarczyk, M Falkowska, Z Micun, I Obuchowska… - Nutrients, 2022 - mdpi.com
Glaucoma is one of the most common causes of irreversible vision loss worldwide. It is an
insidious disease with a multifactorial pathogenesis. Despite progress in treatment methods …

[HTML][HTML] Glaucoma: Novel antifibrotic therapeutics for the trabecular meshwork

M Qin, C Yu-Wai-Man - European Journal of Pharmacology, 2023 - Elsevier
Glaucoma is a chronic and progressive neurodegenerative disease characterized by the
loss of retinal ganglion cells and visual field defects, currently affecting around 1% of the …

[HTML][HTML] Is fat the future for saving sight? Bioactive lipids and their impact on glaucoma

M Kolko, ZA Mouhammad, B Cvenkel - Pharmacology & Therapeutics, 2023 - Elsevier
Glaucoma is characterized by a continuous loss of retinal ganglion cells. The cause of
glaucoma is associated with an increase in intraocular pressure (IOP), but the underlying …

Three major causes of metabolic retinal degenerations and three ways to avoid them

A Kovács-Valasek, T Rák, E Pöstyéni, A Csutak… - International journal of …, 2023 - mdpi.com
An imbalance of homeostasis in the retina leads to neuron loss and this eventually results in
a deterioration of vision. If the stress threshold is exceeded, different protective/survival …

Pharmaceutical approaches to Normal tension Glaucoma

ML Salvetat, F Pellegrini, L Spadea, C Salati… - Pharmaceuticals, 2023 - mdpi.com
Normal tension glaucoma (NTG) is defined as a subtype of primary open-angle glaucoma
(POAG) in which the intraocular pressure (IOP) values are constantly within the statistically …

Optic Nerve Neuroprotection in Glaucoma: A Narrative Review

A D'Angelo, L Vitiello, F Lixi, G Abbinante… - Journal of Clinical …, 2024 - mdpi.com
In recent years, researchers have been interested in neuroprotective therapies as a cutting-
edge therapeutic strategy to treat neurodegenerative disorders by shielding the brain system …

Citicoline/coenzyme Q10/vitamin B3 fixed combination exerts synergistic protective effects on neuronal cells exposed to oxidative stress

L Mastropasqua, L Agnifili, C Ferrante, M Sacchi… - Nutrients, 2022 - mdpi.com
Background: The present study aimed to investigate the rationale and efficacy of using a
citicoline, coenzyme Q10 (CAVAQ10) and vitamin B3 fixed combination in combating …

[HTML][HTML] Nicotinamide: Bright Potential in Glaucoma Management

S Babighian, I Gattazzo, MS Zanella, A Galan… - Biomedicines, 2024 - mdpi.com
Background: Glaucoma is a major cause of incurable ocular morbidity and poses significant
challenges in its management due to the limited treatment options and potential adverse …

Complementary Approaches to Retinal Health Focusing on Diabetic Retinopathy

T Rák, A Kovács-Valasek, E Pöstyéni, A Csutak… - Cells, 2023 - mdpi.com
Diabetes mellitus affects carbohydrate homeostasis but also influences fat and protein
metabolism. Due to ophthalmic complications, it is a leading cause of blindness worldwide …