Long-term cardiovascular consequences of fetal growth restriction: biology, clinical implications, and opportunities for prevention of adult disease
In the modern world, cardiovascular disease is a leading cause of death for both men and
women. Epidemiologic studies consistently have suggested an association between low …
women. Epidemiologic studies consistently have suggested an association between low …
Hypoxia and fetal heart development
AJ Patterson, L Zhang - Current molecular medicine, 2010 - ingentaconnect.com
Fetal hearts show a remarkable ability to develop under hypoxic conditions. The metabolic
flexibility of fetal hearts allows sustained development under low oxygen conditions. In fact …
flexibility of fetal hearts allows sustained development under low oxygen conditions. In fact …
Fetal growth restriction results in remodeled and less efficient hearts in children
Background—Fetal growth restriction (FGR) affects 5% to 10% of newborns and is
associated with increased cardiovascular mortality in adulthood. The most commonly …
associated with increased cardiovascular mortality in adulthood. The most commonly …
Developmental programming of cardiovascular dysfunction by prenatal hypoxia and oxidative stress
Fetal hypoxia is a common complication of pregnancy. It has been shown to programme
cardiac and endothelial dysfunction in the offspring in adult life. However, the mechanisms …
cardiac and endothelial dysfunction in the offspring in adult life. However, the mechanisms …
Developmental programming of cardiovascular disease by prenatal hypoxia
It is now recognized that the quality of the fetal environment during early development is
important in programming cardiovascular health and disease in later life. Fetal hypoxia is …
important in programming cardiovascular health and disease in later life. Fetal hypoxia is …
Early onset fetal growth restriction
Fetal growth restriction (FGR) diagnosed before 32 weeks is identified by fetal smallness
associated with Doppler abnormalities and is associated with significant perinatal morbidity …
associated with Doppler abnormalities and is associated with significant perinatal morbidity …
Assisted reproductive technologies are associated with cardiovascular remodeling in utero that persists postnatally
Background—Assisted reproductive technologies (ARTs) have been shown to be
associated with general vascular dysfunction in late childhood. However, it is unknown …
associated with general vascular dysfunction in late childhood. However, it is unknown …
Intrauterine growth restriction: impact on cardiovascular development and function throughout infancy
Intrauterine growth restriction (IUGR) refers to the situation where a fetus does not grow
according to its genetic growth potential. One of the main causes of IUGR is uteroplacental …
according to its genetic growth potential. One of the main causes of IUGR is uteroplacental …
Cardiovascular programming in children born small for gestational age and relationship with prenatal signs of severity
OBJECTIVE: The objective of the study was to evaluate cardiovascular function in children
who were small-for-gestational-age (SGA) fetuses. STUDY DESIGN: This was a prospective …
who were small-for-gestational-age (SGA) fetuses. STUDY DESIGN: This was a prospective …
Preeclampsia link to gestational hypoxia
W Tong, DA Giussani - Journal of developmental origins of health …, 2019 - cambridge.org
Complications of pregnancy remain key drivers of morbidity and mortality, affecting the
health of both the mother and her offspring in the short and long term. There is lack of …
health of both the mother and her offspring in the short and long term. There is lack of …