Review of potential health risks associated with nanoscopic calcium phosphate

M Epple - Acta biomaterialia, 2018 - Elsevier
Calcium phosphate is applied in many products in biomedicine, but also in toothpastes and
cosmetics. In some cases, it is present in nanoparticulate form, either on purpose or after …

Calciprotein particles: balancing mineral homeostasis and vascular pathology

AG Kutikhin, L Feenstra, AE Kostyunin… - … , and vascular biology, 2021 - Am Heart Assoc
Hypercalcemia and hyperphosphatemia associate with an elevated risk of cardiovascular
events, yet the pathophysiological basis of this association is unclear. Disturbed mineral …

Cellular clearance and biological activity of calciprotein particles depend on their maturation state and crystallinity

S Köppert, A Büscher, A Babler, A Ghallab… - Frontiers in …, 2018 - frontiersin.org
Background: The liver-derived plasma protein fetuin-A is a systemic inhibitor of ectopic
calcification. Fetuin-A stabilizes saturated mineral solutions by forming colloidal protein …

[HTML][HTML] Fetuin-A is a HIF target that safeguards tissue integrity during hypoxic stress

S Rudloff, M Janot, S Rodriguez, K Dessalle… - Nature …, 2021 - nature.com
Intrauterine growth restriction (IUGR) is associated with reduced kidney size at birth,
accelerated renal function decline, and increased risk for chronic kidney and cardiovascular …

Live imaging of calciprotein particle clearance and receptor mediated uptake: role of calciprotein monomers

S Koeppert, A Ghallab, S Peglow… - Frontiers in Cell and …, 2021 - frontiersin.org
Background The liver-derived plasma protein fetuin A is a systemic inhibitor of ectopic
calcification. Fetuin-A stabilizes calcium phosphate mineral initially as ion clusters to form …

Mud in the blood: the role of protein-mineral complexes and extracellular vesicles in biomineralisation and calcification

W Jahnen-Dechent, A Büscher, S Köppert… - Journal of Structural …, 2020 - Elsevier
Protein-mineral interaction is known to regulate biomineral stability and morphology. We
hypothesise that fluid phases produce highly dynamic protein-mineral complexes involved …

Mineral self-organization on a lifeless planet

JM García-Ruiz, MA Van Zuilen, W Bach - Physics of Life Reviews, 2020 - Elsevier
It has been experimentally demonstrated that, under alkaline conditions, silica is able to
induce the formation of mineral self-assembled inorganic-inorganic composite materials …

Calcium carbonate precipitation by Bacillus and Sporosarcina strains isolated from concrete and analysis of the bacterial community of concrete

HJ Kim, HJ Eom, C Park, J Jung, B Shin… - … of Microbiology and …, 2016 - koreascience.kr
Microbially induced calcium carbonate precipitation (CCP) is a long-standing but re-
emerging environmental engineering process for production of self-healing concrete …

Calciprotein particles link disturbed mineral homeostasis with cardiovascular disease by causing endothelial dysfunction and vascular inflammation

DK Shishkova, EA Velikanova, LA Bogdanov… - International journal of …, 2021 - mdpi.com
An association between high serum calcium/phosphate and cardiovascular events or death
is well-established. However, a mechanistic explanation of this correlation is lacking. Here …

Low molecular weight chitosan-coated polymeric nanoparticles for sustained and pH-sensitive delivery of paclitaxel

SA Abouelmagd, YJ Ku, Y Yeo - Journal of drug targeting, 2015 - Taylor & Francis
Low molecular weight chitosan (LMWC) is a promising polymer for surface modification of
nanoparticles (NPs), which can impart both stealth effect and electrostatic interaction with …