Mitochondrial fusion and fission: The fine‐tune balance for cellular homeostasis

M Adebayo, S Singh, AP Singh… - The FASEB …, 2021 - Wiley Online Library
Mitochondria are highly dynamic, maternally inherited cytoplasmic organelles, which fulfill
cellular energy demand through the oxidative phosphorylation system. Besides, they play an …

Mitochondria in disease: changes in shapes and dynamics

BC Jenkins, K Neikirk, P Katti, SM Claypool… - Trends in biochemical …, 2024 - cell.com
Mitochondrial structure often determines the function of these highly dynamic,
multifunctional, eukaryotic organelles, which are essential for maintaining cellular health …

[HTML][HTML] Recent advances in targeted drug delivery strategy for enhancing oncotherapy

J Li, Q Wang, G **a, N Adilijiang, Y Li, Z Hou, Z Fan… - Pharmaceutics, 2023 - mdpi.com
Targeted drug delivery is a precise and effective strategy in oncotherapy that can accurately
deliver drugs to tumor cells or tissues to enhance their therapeutic effect and, meanwhile …

Role of mitochondrial alterations in human cancer progression and cancer immunity

SF Wang, LM Tseng, HC Lee - Journal of biomedical science, 2023 - Springer
Dysregulating cellular metabolism is one of the emerging cancer hallmarks. Mitochondria
are essential organelles responsible for numerous physiologic processes, such as energy …

Mitochondrial-derived damage-associated molecular patterns amplify neuroinflammation in neurodegenerative diseases

M Lin, N Liu, Z Qin, Y Wang - Acta Pharmacologica Sinica, 2022 - nature.com
Both mitochondrial dysfunction and neuroinflammation are implicated in neurodegeneration
and neurodegenerative diseases. Accumulating evidence shows multiple links between …

Mitochondrial dynamics in health and disease

NMB Yapa, V Lisnyak, B Reljic, MT Ryan - FEBS letters, 2021 - Wiley Online Library
In animals, mitochondria are mainly organised into an interconnected tubular network
extending across the cell along a cytoskeletal scaffold. Mitochondrial fission and fusion, as …

Role of mitochondria in radiation responses: epigenetic, metabolic, and signaling impacts

D Averbeck, C Rodriguez-Lafrasse - International journal of molecular …, 2021 - mdpi.com
Until recently, radiation effects have been considered to be mainly due to nuclear DNA
damage and their management by repair mechanisms. However, molecular biology studies …

[HTML][HTML] Reactive oxygen species and mitochondrial dynamics: the yin and yang of mitochondrial dysfunction and cancer progression

J Ježek, KF Cooper, R Strich - Antioxidants, 2018 - mdpi.com
Mitochondria are organelles with a highly dynamic ultrastructure maintained by a delicate
equilibrium between its fission and fusion rates. Understanding the factors influencing this …

Small-molecule fluorogenic probes for mitochondrial nanoscale imaging

R Zhai, B Fang, Y Lai, B Peng, H Bai, X Liu… - Chemical Society …, 2023 - pubs.rsc.org
Mitochondria are inextricably linked to the development of diseases and cell metabolism
disorders. Super-resolution imaging (SRI) is crucial in enhancing our understanding of …

Mitochondria-targeted fluorophore: State of the art and future trends

Q Ding, X Wang, Y Luo, X Leng, X Li, M Gu… - Coordination Chemistry …, 2024 - Elsevier
Mitochondria, pivotal organelles responsible for cellular energy production and behavioral
regulation, play a crucial role in various diseases, notably cancer. Mitochondria-targeting …