Action mechanisms and research methods of tRNA-derived small RNAs
Y **e, L Yao, X Yu, Y Ruan, Z Li, J Guo - Signal transduction and …, 2020 - nature.com
Abstract tRNA-derived small RNAs (tsRNAs), including tRNA-derived fragments (tRFs) and
tRNA halves (tiRNAs), are small regulatory RNAs processed from mature tRNAs or …
tRNA halves (tiRNAs), are small regulatory RNAs processed from mature tRNAs or …
The life and times of a tRNA
The study of eukaryotic tRNA processing has given rise to an explosion of new information
and insights in the last several years. We now have unprecedented knowledge of each step …
and insights in the last several years. We now have unprecedented knowledge of each step …
Circulating cell-free nucleic acids: main characteristics and clinical application
Liquid biopsy recently became a very promising diagnostic method that has several
advantages over conventional invasive methods. Liquid biopsy may serve as a source of …
advantages over conventional invasive methods. Liquid biopsy may serve as a source of …
tRNA-derived fragments in Alzheimer's disease: implications for new disease biomarkers and neuropathological mechanisms
Background: Alzheimer's disease (AD) is the most common type of dementia caused by
irreversible neurodegeneration, with the onset mechanisms elusive. tRNA-derived RNA …
irreversible neurodegeneration, with the onset mechanisms elusive. tRNA-derived RNA …
tRNA-derived fragments: A new class of non-coding RNA with key roles in nervous system function and dysfunction
Abstract tRNA-derived small RNAs (tsRNA) are a recently identified family of non-coding
RNA that have been associated with a variety of cellular functions including the regulation of …
RNA that have been associated with a variety of cellular functions including the regulation of …
m5U54 tRNA Hypomodification by Lack of TRMT2A Drives the Generation of tRNA-Derived Small RNAs
M Pereira, DR Ribeiro, MM Pinheiro, M Ferreira… - International Journal of …, 2021 - mdpi.com
Transfer RNA (tRNA) molecules contain various post-transcriptional modifications that are
crucial for tRNA stability, translation efficiency, and fidelity. Besides their canonical roles in …
crucial for tRNA stability, translation efficiency, and fidelity. Besides their canonical roles in …
A mouse tissue atlas of small noncoding RNA
Small noncoding RNAs (ncRNAs) play a vital role in a broad range of biological processes
both in health and disease. A comprehensive quantitative reference of small ncRNA …
both in health and disease. A comprehensive quantitative reference of small ncRNA …
The tRNA regulome in neurodevelopmental and neuropsychiatric disease
Abstract Transfer (t) RNAs are 70–90 nucleotide small RNAs highly regulated by 43 different
types of epitranscriptomic modifications and requiring aminoacylation ('charging') for mRNA …
types of epitranscriptomic modifications and requiring aminoacylation ('charging') for mRNA …
tRNA derived small RNAs—Small players with big roles
S George, M Rafi, M Aldarmaki, M ElSiddig… - Frontiers in …, 2022 - frontiersin.org
In the past 2 decades, small non-coding RNAs derived from tRNA (tsRNAs or tRNA derived
fragments; tRFs) have emerged as new powerful players in the field of small RNA mediated …
fragments; tRFs) have emerged as new powerful players in the field of small RNA mediated …
tRNA-derived small RNAs: novel insights into the pathogenesis and treatment of cardiovascular diseases
S Wang, Z Luo, L Yuan, X Lin, Y Tang, L Yin… - Journal of …, 2023 - Springer
Abstract tRNA-derived small RNAs (tsRNAs) are non-coding RNAs with diverse functions in
various diseases. Although research on tsRNAs has focused on their roles in cancer, such …
various diseases. Although research on tsRNAs has focused on their roles in cancer, such …