Metal ions are essential to many chemical, biological, and environmental processes. In the
past two decades, many DNA-based metal sensors have emerged. While the main …

Since the initial discovery of ribozymes in the early 1980s, catalytic nucleic acids have been
used in different areas. Compared with protein enzymes, catalytic nucleic acids are …

Silver is a very common heavy metal, and its detection is of significant analytical importance.
DNAzymes are DNA-based catalysts; they typically recruit divalent and trivalent metal ions …

Cu2+ is a very important metal ion in biology, environmental science, and industry.
Develo** biosensors for Cu2+ is a key topic in analytical chemistry. DNAzyme-based …

Lanthanides are very important for their unique catalytic, optical and magnetic properties.
Various ligands have been synthesized to coordinate with lanthanides so that their …

Ca2+ is a highly important metal ion in biology and in the environment, and thus there is
extensive work in develo** sensors for Ca2+ detection. Although many Ca2+‐binding …

Most previously reported RNA-cleaving DNAzymes require only a single divalent metal ion
for catalysis. We recently reported a general trivalent lanthanide-dependent DNAzyme …

Phosphorothioate (PS) modification replaces one of the non-bridging oxygen atoms by
sulfur in the phosphate backbone of nucleic acids. While PS DNAs have been traditionally …

DNAzymes are in vitro selected DNA oligonucleotides with catalytic activities. RNA cleavage
is one of the most extensively studied DNAzyme reactions. To expand the chemical …

Chromium is a very important analyte for environmental monitoring, and develo**
biosensors for chromium is a long‐standing analytical challenge. In this work, in vitro …