Circulating cell-free nucleic acids: main characteristics and clinical application
Liquid biopsy recently became a very promising diagnostic method that has several
advantages over conventional invasive methods. Liquid biopsy may serve as a source of …
advantages over conventional invasive methods. Liquid biopsy may serve as a source of …
Circulating tumor DNA as a liquid biopsy for cancer
BACKGROUND Targeted therapies have markedly changed the treatment of cancer over
the past 10 years. However, almost all tumors acquire resistance to systemic treatment as a …
the past 10 years. However, almost all tumors acquire resistance to systemic treatment as a …
The biology of circulating tumor cells
Metastasis is a biologically complex process consisting of numerous stochastic events which
may tremendously differ across various cancer types. Circulating tumor cells (CTCs) are …
may tremendously differ across various cancer types. Circulating tumor cells (CTCs) are …
Circulating tumor DNA and liquid biopsy: opportunities, challenges, and recent advances in detection technologies
Cell-free DNA (cfDNA) refers to short fragments of acellular nucleic acids detectable in
almost all body fluids, including blood, and is involved in various physiological and …
almost all body fluids, including blood, and is involved in various physiological and …
Inferring expressed genes by whole-genome sequencing of plasma DNA
The analysis of cell-free DNA (cfDNA) in plasma represents a rapidly advancing field in
medicine. cfDNA consists predominantly of nucleosome-protected DNA shed into the …
medicine. cfDNA consists predominantly of nucleosome-protected DNA shed into the …
Emerging concepts in liquid biopsies
S Perakis, MR Speicher - BMC medicine, 2017 - Springer
Characterizing and monitoring tumor genomes with blood samples could achieve significant
improvements in precision medicine. As tumors shed parts of themselves into the circulation …
improvements in precision medicine. As tumors shed parts of themselves into the circulation …
Circulating tumor DNA as biomarkers for cancer detection
X Han, J Wang, Y Sun - Genomics, Proteomics and …, 2017 - academic.oup.com
Detection of circulating tumor DNAs (ctDNAs) in cancer patients is an important component
of cancer precision medicine ctDNAs. Compared to the traditional physical and biochemical …
of cancer precision medicine ctDNAs. Compared to the traditional physical and biochemical …
Dissecting tumor growth: the role of cancer stem cells in drug resistance and recurrence
B Aramini, V Masciale, G Grisendi, F Bertolini, M Maur… - Cancers, 2022 - mdpi.com
Simple Summary Cancer is one of the most debated problems all over the world. Cancer
stem cells are considered responsible of tumor initiation, metastasis, drug resistance, and …
stem cells are considered responsible of tumor initiation, metastasis, drug resistance, and …
Normal and cancerous tissues release extrachromosomal circular DNA (eccDNA) into the circulation
Cell-free circulating linear DNA is being explored for noninvasive diagnosis and
management of tumors and fetuses, the so-called liquid biopsy. Previously, we observed the …
management of tumors and fetuses, the so-called liquid biopsy. Previously, we observed the …
Potential utility of liquid biopsy as a diagnostic and prognostic tool for the assessment of solid tumors: implications in the precision oncology
Liquid biopsy is a technique that utilizes circulating biomarkers in the body fluids of cancer
patients to provide information regarding the genetic landscape of the cancer. It is emerging …
patients to provide information regarding the genetic landscape of the cancer. It is emerging …