Blood biomarkers for stroke diagnosis and management
Biomarkers are objective indicators used to assess normal or pathological processes,
evaluate responses to treatment and predict outcomes. Many blood biomarkers already …
evaluate responses to treatment and predict outcomes. Many blood biomarkers already …
Inflammation, autoimmunity, infection, and stroke: epidemiology and lessons from therapeutic intervention
712 Stroke March 2020 outcome of stroke. 27, 28 Rosuvastatin reduced stroke risk in
subjects who either achieved LDL-C levels of< 70 mg/dL or hs-CRP levels of< 2 mg/L …
subjects who either achieved LDL-C levels of< 70 mg/dL or hs-CRP levels of< 2 mg/L …
Colchicine in patients with acute ischaemic stroke or transient ischaemic attack (CHANCE-3): multicentre, double blind, randomised, placebo controlled trial
Objectives To assess the efficacy and safety of colchicine versus placebo on reducing the
risk of subsequent stroke after high risk non-cardioembolic ischaemic stroke or transient …
risk of subsequent stroke after high risk non-cardioembolic ischaemic stroke or transient …
Interleukin-6 and YKL-40 predicted recurrent stroke after ischemic stroke or TIA: analysis of 6 inflammation biomarkers in a prospective cohort study
J Li, J Lin, Y Pan, M Wang, X Meng, H Li… - Journal of …, 2022 - Springer
Objective Contribution of individual and combined inflammatory markers in prognosis after
stroke was still undefined. We aimed to investigate the association of systemic and local …
stroke was still undefined. We aimed to investigate the association of systemic and local …
Atherosclerosis and multi-organ-associated pathologies
WC Keeter, S Ma, N Stahr, AK Moriarty… - Seminars in …, 2022 - Springer
Atherosclerosis is a chronic inflammatory disease of the vascular system that is
characterized by the deposition of modified lipoproteins, accumulation of immune cells, and …
characterized by the deposition of modified lipoproteins, accumulation of immune cells, and …
C-Reactive Protein, Interleukin-6, and Vascular Recurrence According to Stroke Subtype: An Individual Participant Data Meta-Analysis
Background and Objectives Anti-inflammatory therapies reduce major adverse
cardiovascular events (MACE) in coronary artery disease but remain unproven after stroke …
cardiovascular events (MACE) in coronary artery disease but remain unproven after stroke …
[HTML][HTML] Residual inflammatory risk predicts poor prognosis in acute ischemic stroke or transient ischemic attack patients
J Li, Y Pan, J Xu, S Li, M Wang, K Quan, X Meng, H Li… - Stroke, 2021 - journals.lww.com
Background and Purpose: It is still unclear whether the residual cholesterol and
inflammatory risk in the acute phase is associated with prognosis of stroke. We aimed to …
inflammatory risk in the acute phase is associated with prognosis of stroke. We aimed to …
Mediation of systemic inflammation on insulin resistance and prognosis of nondiabetic patients with ischemic stroke
A **, S Wang, J Li, M Wang, J Lin, H Li, X Meng… - Stroke, 2023 - Am Heart Assoc
Background: Insulin resistance is associated with stroke recurrence and poor functional
outcomes of nondiabetic patients with ischemic stroke. The study aimed to investigate …
outcomes of nondiabetic patients with ischemic stroke. The study aimed to investigate …
Interleukin-6, C-reactive protein, fibrinogen, and risk of recurrence after ischaemic stroke: systematic review and meta-analysis
JJ McCabe, E O'reilly, S Coveney… - European stroke …, 2021 - journals.sagepub.com
Background Recent randomised trials showed benefit for anti-inflammatory therapies in
coronary disease but excluded stroke. The prognostic value of blood inflammatory markers …
coronary disease but excluded stroke. The prognostic value of blood inflammatory markers …
Anti-inflammatory approaches to ischaemic stroke prevention
PJ Kelly, S Murphy, S Coveney, F Purroy… - Journal of Neurology …, 2018 - jnnp.bmj.com
Stroke is a major cause of neurological morbidity and mortality. Atherosclerosis is a major
contributor to first and recurrent stroke. A growing evidence base indicates that inflammation …
contributor to first and recurrent stroke. A growing evidence base indicates that inflammation …