Role of comorbidities in heart failure prognosis Part 2: Chronic kidney disease, elevated serum uric acid

A Tedeschi, P Agostoni, B Pezzuto… - European journal of …, 2020 - journals.sagepub.com
Despite improvements in pharmacotherapy, morbidity and mortality rates in community-
based populations with chronic heart failure still remain high. The increase in medical …

Xanthine oxidase and uric acid in cardiovascular disease: clinical impact and therapeutic options

W Doehner, U Landmesser - Seminars in nephrology, 2011 - Elsevier
The association between increased uric acid (UA) levels and cardiovascular disease (CVD)
has been observed and studied for many decades. The value of UA as an independent …

Hyperuricemia and incident heart failure

E Krishnan - Circulation: Heart Failure, 2009 - Am Heart Assoc
Background—Hyperuricemia, a known correlate of oxidative stress, is a marker for adverse
prognosis among individuals with heart failure. However, the relationship between …

Uric acid as a prognostic factor and critical marker of COVID-19

G Li, X Wu, C Zhou, Y Wang, B Song, X Cheng… - Scientific Reports, 2021 - nature.com
The purpose of this study is to explore whether uric acid (UA) can independently act as a
prognostic factor and critical marker of the 2019 novel corona virus disease (COVID-19). A …

Advanced glycation end-products: modifiable environmental factors profoundly mediate insulin resistance

MS Ottum, AM Mistry - Journal of clinical biochemistry and nutrition, 2015 - jstage.jst.go.jp
抄録 Advanced glycation end-products are toxic by-products of metabolism and are also
acquired from high-temperature processed foods. They promote oxidative damage to …

Relation of serum uric acid levels and outcomes among patients hospitalized for worsening heart failure with reduced ejection fraction (from the efficacy of vasopressin …

M Vaduganathan, SJ Greene, AP Ambrosy… - The American Journal of …, 2014 - Elsevier
We investigated the clinical profiles associated with serum uric acid (sUA) levels in a large
cohort of patients hospitalized for worsening chronic heart failure with ejection fraction …

Systemic oxidative stress in older patients with mild cognitive impairment or late onset Alzheimer's disease

C Cervellati, E Cremonini, C Bosi… - Current Alzheimer …, 2013 - ingentaconnect.com
A large body of evidences obtained in human and animal brain tissue suggest a role of
oxidative stress (OxS) in the pathogenesis of late onset Alzheimer's disease (LOAD); on the …

Serum superoxide dismutase is associated with vascular structure and function in hypertensive and diabetic patients

MA Gómez-Marcos… - Oxidative Medicine …, 2016 - Wiley Online Library
Oxidative stress is associated with cardiac and vascular defects leading to hypertension and
atherosclerosis, being superoxide dismutase (SOD) one of the main intracellular antioxidant …

Extracellular superoxide dismutase is associated with left ventricular geometry and heart failure in patients with cardiovascular disease

X Li, Y Lin, S Wang, S Zhou, J Ju, X Wang… - Journal of the …, 2020 - Am Heart Assoc
Background Extracellular superoxide dismutase (Ec‐SOD) is a major scavenger of reactive
oxygen species. However, its relationships with abnormal left ventricular (LV) geometry …

Uric acid in heart failure: a biomarker or therapeutic target?

M Kaufman, M Guglin - Heart failure reviews, 2013 - Springer
There is a need for a cost-effective prognostic biomarker in heart failure (HF). Substantial
evidence suggests that uric acid (UA) is an independent marker for adverse prognosis in …