Sarcopenia is of important clinical relevance for loss of independence in older adults. The
prevalence of obesity in combination with sarcopenia ('sarcopenic-obesity') is increasing at …

Anabolic resistance is defined by a blunted stimulation of muscle protein synthesis rates
(MPS) to common anabolic stimuli in skeletal muscle tissue such as dietary protein and …

Summary The European Society for Clinical Nutrition and Metabolism (ESPEN) and the
European Association for the Study of Obesity (EASO) launched the Sarcopenic Obesity …

Maximizing the post-exercise increase in muscle protein synthesis, especially of the
contractile myofibrillar protein fraction, is essential to facilitate effective muscle remodelling …

Background: The “leucine trigger” hypothesis was originally conceived to explain the post-
prandial regulation of muscle protein synthesis (MPS). This hypothesis implicates the …

Age-related loss of muscle mass, strength, and performance, commonly referred to as
sarcopenia, has wide-ranging detrimental effects on human health, the ramifications of …

Background Dietary protein ingestion augments post (resistance) exercise muscle protein
synthesis (MPS) rates. It is thought that the dose of leucine ingested within the protein …

Background Muscle atrophy and strength loss are common adverse outcomes following
bariatric surgery. This randomized, controlled trial investigated the effects of exercise …

Improving the health of skeletal muscle is an important component of obesity treatment.
Apart from allowing for physical activity, skeletal muscle tissue is fundamental for the …

Preserving skeletal muscle mass and functional capacity is essential for healthy ageing.
Transient periods of disuse and/or inactivity in combination with sub-optimal dietary intake …