Backstage players of fibrosis: NOX4, mTOR, HDAC, and S1P; companions of TGF-β

AP Jiménez-Uribe, T Gomez-Sierra, OE Aparicio-Trejo… - Cellular …, 2021 - Elsevier
The fibrotic process could be easily defined as a pathological excess of extracellular matrix
deposition, leading to disruption of tissue architecture and eventually loss of function; …

Targeting growth factor and cytokine pathways to treat idiopathic pulmonary fibrosis

H Ma, S Liu, S Li, Y **a - Frontiers in Pharmacology, 2022 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease of unknown origin
that usually results in death from secondary respiratory failure within 2–5 years of diagnosis …

Proteomic biomarkers of progressive fibrosing interstitial lung disease: a multicentre cohort analysis

WS Bowman, CA Newton, AL Linderholm… - The Lancet …, 2022 - thelancet.com
Background Progressive fibrosing interstitial lung disease (ILD) is characterised by
parenchymal scar formation, leading to high morbidity and mortality. The ability to predict …

The regenerative power of stem cells: treating bleomycin-induced lung fibrosis

A Vats, P Chaturvedi - Stem Cells and Cloning: Advances and …, 2023 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease with no known
cure, characterized by the formation of scar tissue in the lungs, leading to respiratory failure …

Update in interstitial lung disease 2020

AJ Podolanczuk, AW Wong, S Saito… - American Journal of …, 2021 - atsjournals.org
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–
induced coronavirus disease (COVID-19) dominated the year 2020. Initial reports of the long …

Epithelial–mesenchymal transition: a major pathogenic driver in idiopathic pulmonary fibrosis?

F Salton, B Ruaro, P Confalonieri, M Confalonieri - Medicina, 2020 - mdpi.com
Medicina | Free Full-Text | Epithelial–Mesenchymal Transition: A Major Pathogenic Driver in
Idiopathic Pulmonary Fibrosis? Next Article in Journal Vertical Bone Gain after Sinus Lift …

The ANGPTL4-HIF-1α loop: a critical regulator of renal interstitial fibrosis

Y Li, S Chen, Q Yang, X Liu, W Zhou, T Kang… - Journal of translational …, 2024 - Springer
Background Renal interstitial fibrosis (RIF) is a progressive, irreversible terminal kidney
disease with a poor prognosis and high mortality. Angiopoietin-like 4 (ANGPTL4) is known …

Novel mediators of idiopathic pulmonary fibrosis

S Saito, B Deskin, M Rehan, S Yadav… - Clinical …, 2022 - portlandpress.com
Fibrosis involving the lung may occur in many settings, including in association with known
environmental agents, connective tissue diseases, and exposure to drugs or radiation …

Understanding idiopathic pulmonary fibrosis-clinical features, molecular mechanism and therapies

GS Suri, G Kaur, CK Jha, M Tiwari - Experimental gerontology, 2021 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic lung fibrosing disease with high prevalence
that has a prognosis worse than many cancers. There has been a recent influx of new …

Molecular regulation of skeletal muscle growth and organelle biosynthesis: practical recommendations for exercise training

R Solsona, L Pavlin, H Bernardi… - International Journal of …, 2021 - mdpi.com
The regulation of skeletal muscle mass and organelle homeostasis is dependent on the
capacity of cells to produce proteins and to recycle cytosolic portions. In this investigation …