Microglia are the resident macrophages of the central nervous system (CNS) that control
brain development, maintain neural environments, respond to injuries, and regulate …

PIEZO1 is a eukaryotic membrane protein that assembles as trimers to form calcium‐
permeable, non‐selective cation channels with exquisite capabilities for mechanical force …

Spontaneous Ca2+ transients of neural cells is a hallmark of the develo** nervous
system. It is widely accepted that chemical signals, like neurotransmitters, contribute to …

The structural development of the heart depends heavily on mechanical forces, and rhythmic
contractions generate essential physical stimuli during morphogenesis. Cardiac cells play a …

Background As physical signals, mechanical cues regulate the neural cells in the brain. The
mechanosensitive channels (MSCs) perceive the mechanical cues and transduce them by …

Mechanotransduction is the process whereby cells convert mechanical signals into
electrochemical responses, where mechanosensitive proteins mediate this interaction. To …

PIEZO1 is critical to numerous physiological processes, transducing diverse mechanical
stimuli into electrical and chemical signals. Recent studies underscore the importance of …

ABSTRACT In 2022, Development launched its Pathway to Independence (PI) Programme,
aimed at supporting postdocs as they transition to their first independent position. We …

Compared to the well-established functions of sympathetic innervation, the role of sensory
afferents in adipose tissues remains less understood. Recent work revealed the anatomical …

Communication between cells is necessary for the proper formation of tissues. The nervous
system is no exception. During development of the nervous system, neurons and glia are in …